Enhancement of the serum chloride concentration by administration of sodium–glucose cotransporter-2 inhibitor and its mechanisms and clinical significance in type 2 diabetic patients: a pilot study

Table 1 Clinical characteristics of the study patients at baseline

Characteristics	n = 10
Age, years (mean ± SD)	61.7 ± 14 (36–92)
Male	4
Body mass index (kg/m²)	32.1 ± 3.7 (28.2–40)
eGFR (mL min⁻¹·1.73 m⁻²)	76.3 ± 14.4 (51–90)
Cardiovascular disease
Hypertension	7
Hyperlipidemia	6
Ischemic heart disease	1
Medication for cardiovascular disease
ACE inhibitors/ARB	5
Beta-blockers	2
Calcium antagonists	5
Nitrate	1
Diuretics	0
Lipid-lowering drugs	7
Therapy for diabetes
Metformin	5
Sulfonylureas	2
Dipetidyl peptidase-4 inhibitors	7
Thiazolidinediones	0
Glucagon-like peptide-1 antagonist	0
Insulin	2

Data presented as number (%) of patients otherwise specified. eGFR estimated glomerular filtration rate, ACE angiotensin-converting enzyme, ARB angiotensin II receptor blocker

ISSN: 1758-5996