Overall reduced lymphocyte especially T and B subsets closely related to the poor prognosis and the disease severity in severe patients with COVID-19 and diabetes mellitus

Table 4 Spearman correlation analysis of disease severity, virus negative conversion time, prognosis, baseline lymphocyte subset counts, age and DM(n = 95)

Variable	Disease severity (1 = common, 2 = severe, 3 = critically ill)		Virus negative conversion time(days)		Prognosis (1 = cure, 2 = unhealed, 3 = death)
Variable	r	p	r	p	R	p
DM (1 = without, 2 = with)	0.320	< 0.0001	0.337	0.001
Age (year)	0.361	< 0.0001	0.264	0.010	0.263	0.010
LY (cells/μl)	–0.341	0.001
LY% (%)	–0.371	< 0.0001			–0.209	0.042
CD3+ (cells/μl)	–0.379	< 0.0001
CD3+ CD4+ (cells/μl)	–0.388	< 0.0001
CD3+ CD8 + (cells/μl)	–0.351	< 0.0001
CD+ 3% (%)	–0.302	0.003
CD3+ CD4+ (%)	–0.219	0.033
CD19 + (cells/μl)	–0.266	0.033
Disease severity (1 = common, 2 = severe, 3 = critically ill)					0.331	0.001
Virus negative conversion time(days)					0.299	0.003

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