Effects of dapagliflozin on serum and urinary uric acid levels in patients with type 2 diabetes: a prospective pilot trial

Table 2 Comparison of urinary parameters

Parameters	Control	Dapagliflozin 10 mg		P-value
Parameters	Control	Before	After	Con vs Bef	Bef vs Aft
24-h UUA (mmol)	3.26 ± 1.29	3.53 ± 0.61	3.79 ± 1.05	0.626	0.567
24-h UNa (mmol)	174.57 ± 46.13	126.18 ± 18.89	129.61 ± 27.34	0.025	0.057
24-h UCl (mmol)	167.71 ± 53.83	129.61 ± 27.34	177.00 ± 36.43	0.125	0.055
FEUA	0.047 ± 0.044	0.062 ± 0.009	0.093 ± 0.029	0.460	0.035
FENa	4.75 ± 4.46	5.58 ± 1.19	8.35 ± 2.63	0.672	0.022
FECl	6.63 ± 6.39	7.84 ± 2.27	11.71 ± 3.74	0.674	0.015

Con, control; Bef, before; Aft, after; UUA, urinary uric acid; UNa, urinary sodium; UCl, urinary chloride; FEUA, fractional excretion of uric acid; FENa, fractional excretion of sodium; FECl, fractional excretion of chloride

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