Metabolic syndrome and the incidence of lung cancer: a meta-analysis of cohort studies

Table 1 Characteristics of the included cohort studies

Study	Country	Design	Characteristics of the participants	Number of participants	Diagnostic criteria of MetS	Follow-up period	Diagnosis of lung cancer	Number of lung cancer cases	Outcome reported	Variables adjusted
Russo 2008	Italy	PC	Community based population	16,677	NCEP-ATP III	1999–2005	Local Cancer Registry	118	M, F, T	Age, gender
Inoue 2009	Japan	PC	Community based population	27,724	NCEP-ATP III and IDF	1990–2014	National cancer registries	224	M, F	Age, study area, smoking status, alcohol intake, daily total physical activity level, and TC
Osaki 2012	Japan	RC	General health examinees	38,832	NCEP-ATP III and IDF	1992–2007	Tottori prefectural cancer registry	211	M, F	Age, smoking status, alcohol intake
Kruijsdijk 2013	the Netherlands	PC	Patients with vascular diseases	6172	NCEP-ATP III	1996–2011	Netherlands Cancer Registry	118	T	Age, gender, smoking status, alcohol intake
Ko 2016	Korea	RC	National sample cohort for health check-up	99,565	NCEP-ATP III	2002–2013	Local Cancer Registry	624	M, F	Age, gender, smoking status, alcohol intake, and exercise

NOS the Newcastle–Ottawa Scale, PC prospective cohort, RC retrospective cohort, MetS metabolic syndrome, NCEP-ATP III National Cholesterol Education Program’s Adults Treatment Panel III, IDF International Diabetes Federation, M male, F female, T total, TC total cholesterol

ISSN: 1758-5996