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Table 4 Predicting factors for death of the COVID-19 in patients with DM, only DM, CVD, and only CVD

From: Risk and predictors of in-hospital mortality from COVID-19 in patients with diabetes and cardiovascular disease

Variable

In patients with DM (all), N = 267

In patients with CVD, N = 314

In patients with only CVD, N = 168

In patients with only DM, N = 138

Crude OR OR (95% CI)

Adjusted OR (95% CI)

Crude OR OR (95% CI)

Adjusted OR (95% CI)

Crude OR OR (95% CI)

Adjusted OR (95% CI)

Crude OR OR (95% CI)

Addjusted OR (95% CI)

Age

1.06 (1.03–1.08)*

1.05 (1.02–1.07)*

1.22 (1.06–1.41)*

1.04 (1.01–1.08)*

1.11 (1.02–1.20)*

1.04 (1.00–1.07)

 

Sex (M/F)

1.17 (0.62–2.20)

1.37 (0.78–2.44)

1.43 (0.64–3.16)

 

1.88 (0.72–4.91)#

 

Presence of Other comorbidities

1.26 (0.67–2.34)

0.99 (0.56–1.78)

Laboratory finding

        

WBC count, × 109 per L,

1.54 (1.23–1.92)*

1.35 (1.16–1.58)*

1.04 (0.97–1.12)

1.34 (1.03–1.76)*

 

Lymphocyte count, × 109/L

0.58 (0.51–0.66)*

0.81 (0.71–0.93)*

0.63 (0.56–0.68)*

0.71 (0.54–0.93)*

0.62 (0.54–0.71)*

0.68 (0.56–0.81)*

0.59 (*0.49–0.71)

0.74 (0.59–0.94)*

Neutrophils, × 109/Ml

1.21 (1.13–1.29)*

1.28 (1.19–1.37)*

1.47 (1.29–1.67)*

 

1.18 (1.09–1.28)*

AST, U/L

1.17 (1.10–1.24)*

1.40 (1.29–1.51)*

1.15 (0.99–1.37)

1.48 (1.32–1.66)*

 

1.05 (1.00–1.10)#

ALT, U/L

1.03 (0.99–1.05)#

1.33 (1.18–1.49)

 

1.32 (1.10–1.60)*

 

1.00 (0.99–1.03)#

Albumin, g/L

0.64 (0.58–0.71)*

0.56 (0.50–0.64)

0.68 (0.50–0.92)*

0.61 (0.53–0.70)*

0.76 (0.53–0.86)*

0.75 (0.67–0.83)*

Creatinine, mg/dl

1.46 (1.23–1.78)*

12.72 (1.87–86.70)*

1.03 (0.65–1.61)

1.27 (0.25–6.32)

 

2.02 (0.72–5.7)#

LDH, U/L

102 (1.01–1.03)*

1.03 (1.02–1.04)*

1.02 (1.01–1.03)

 

1.02 (1.01–1.03)*

CRP

1.09 (1.07–1.11)*

1.02 (1.0–1.04)

1.13 (1.10–1.55)

1.14 (1.09–1.18)*

1.09 (1.04–1.14)*

1.08 (1.05–1.11)*

1.03 (1.00–1.06)

Esr, mm/h

1.04 (1.01–1.06)*

1.05 (1.02–1.08)

1.05 (1.01–1.10)*

 

1.02 (0.99–1.05)#

Hb, g/dL

0.54 (0.40–0.75)*

0.39 (0.27–0.57)*

0.28 (0.15–0.52)*

 

0.61 (0.42–90)*

  1. DM (all): DM with or without other comorbidities. “Only DM”: DM without other comorbidities. CVD (all): CVD with or without other comorbidities. “Only CVD”: CVD without other comorbidities. “Any comorbidity”: The presence of any comorbidity
  2. OR odds ratio, CI confidence interval, CVD cardiovascular diseases, DM diabetes mellitus, IQR inter quartile range, ALT alanine transaminases, AST aspartate transaminases, CRP C-reactive protein, Esr erythrocyte sedimentation rate, Hb Hemoglobin, LDH lactate dehydrogenase, PT prothrombin time, WBC white blood cell
  3. *P-value < 0.05; # P-value < 0.20;  all variables with P < 0.2 in the univariate model were included in multivariate model