From: Plasma biomarkers of small intestine adaptations in obesity-related metabolic alterations
Dependent variables | Independent variables | Partiala (r2 × 100) | Total (r2 × 100) | p values |
---|---|---|---|---|
Complete sample | ||||
Citrulline (µmol/L) (n = 214) | GFR (mL/min/m2) | 8.9 | 14.3 | p < 0.001 |
BMI (kg/m2) | 3.7 |  | p < 0.01 | |
T2D diagnosis | 1.7 |  | p < 0.05 | |
I-FABP (pg/mL) (n = 220) | T2D diagnosis | 5.5 | 5.5 | p < 0.001 |
I-FABP/citrulline (n = 218) | T2D diagnosis | 9.9 | 9.9 | p < 0.001 |
Men without diabetes | ||||
Citrulline (µmol/L) (n = 147) | GFR (mL/min/m2) | 10.5 | 14.5 | p < 0.001 |
HOMA-IR | 4.0 |  | p < 0.01 | |
I-FABP (pg/mL) (n = 153) | – | – | – | NS |
I-FABP/citrulline (n = 151) | HOMA-IR | 3.2 | 3.2 | p < 0.05 |