Number of components | Trend P | ||||||
---|---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | 4 | 5 | ||
Cases, n | 218,603 | 385,479 | 455,944 | 426,612 | 303,566 | 116,759 | |
Follow-up duration (person-years) | 31,043,596.21 | 28,642,155.32 | 20,577,529.59 | 12,419,916.48 | 5,887,174.59 | 1,415,272.2 | |
Crude incidence rate (per 1000 person-years) | 7.0418 | 13.4584 | 22.1574 | 34.349 | 51.564 | 82.4993 | |
Age- and sex-adjusted incidence rate (per 1000 person-years) | 10.8634 | 15.5303 | 21.3481 | 29.1435 | 38.6941 | 56.6539 | |
Adjusted HRa (95% CI) | 1 (ref.) | 1.401 (1.394,1.409) | 1.862 (1.852,1.872) | 2.47 (2.456,2.484) | 3.164 (3.144,3.184) | 4.501 (4.466,4.537) | < 0.0001 |