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Table 2 Comparison between patients with rheumatoid arthritis (RA) with abnormal TyG

From: Fasting triglycerides and glucose index: a useful screening test for assessing insulin resistance in patients diagnosed with rheumatoid arthritis and systemic lupus erythematosus

Variables

RA

Abnormal TyG Index

n = 48

RA

Normal TyG index

n = 47

p

Age (years) mean ± SD

54.0 ± 6.8

53.8 ± 7.5

0.8

Disease duration (years), mean ± SD

10.8 ± 8.9

12.9 ± 9.2

0.2

Smoking, n (%)

6 (12.5)

3 (6.7)

0.4

Sedentary lifestyle, n (%)

33 (68.8)

26 (55.3)

0.2

Hypertension, n (%)

19 (39.6)

13 (27.7)

0.2

Duration of hypertension (years), mean ± SD

4.8 ± 8.5

1.7 ± 3.9

0.02

Menopause, n (%)

42 (87.5)

36 (76.6)

0.1

Body mass index (kg/m2), mean ± SD

28.4 ± 3.4

27.5 ± 3.7

0.2

Waist (cm), mean ± SD

94.1 ± 8.1

89.0 ± 10.2

0.008

Total-cholesterol (mg/dL), mean ± SD

207.2 ± 42.1

185.8 ± 29.7

0.005

 Total-cholesterol (mmol/L), mean ± SD

5.3 ± 1.0

4.8 ± 0.7

0.005

HDL-cholesterol (mg/dL), mean ± SD

47.5 ± 13.9

57.1 ± 13.5

0.001

 HDL-cholesterol (mmol/L), mean ± SD

1.2 ± 0.3

1.4 ± 0.3

0.001

LDL-cholesterol (mg/dL), mean ± SD

122.6 ± 36.6

107.3 ± 27.3

0.02

 LDL-cholesterol (mmol/L), mean ± SD

3.1 ± 0.9

2.7 ± 0.7

0.02

Uric acid(mg/dL), mean ± SD

4.6 ± 1.1

4.1 ± 1.3

0.07

 Uric acid(mmol/L), mean ± SD

2.7 ± 0.6

2.4 ± 0.7

0.07

Fat mass% (DXA results), mean ± SD

46.9 ± 4.6

46.8 ± 5.1

0.8

Treatments

 Corticosteroid, n (%)

34 (70.8)

40 (85.1)

0.1

 Chloroquine, n (%)

7 (14.5)

7 (14.8)

0.09

 Methotrexate, n (%)

25 (53.2)

30 (63.8)

0.2

 Leflunomide, n (%)

14 (29.2)

13 (27.7)

1.0

 Biologics, n (%)

4 (8.3)

2 (4.3)

0.4

  1. Italic values indicate significance of p value (p < 0.05)
  2. An abnormal TyG index (TyG index > 4.68) suggests insulin resistance; HDL-cholesterol high density lipoprotein-cholesterol, LDL-cholesterol low density lipoprotein-cholesterol, DXA dual-energy X-ray absortiometry, TyG values are expressed in mean and standard deviation SD; comparisons between proportions were calculated by Χ2 test or Fisher´s exact test; comparisons between means by unpaired Student-t test; biologics included in the analysis: adalimumab, rituximab, infliximab