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Table 2 CpG Sites with highest  % methylation differences and corresponding gene expression

From: Comparison of visceral adipose tissue DNA methylation and gene expression profiles in female adolescents with obesity

Gene symbolProbe IDCpG locationp-value (Ob vs. L)Methylation difference (Ob − L)Probeset IDp-value (Ob vs. L)Fold change
NEDD4Lcg18971282b5′UTR<0.01−16.6212448_at0.033.68
MAPTcg18228076b5′UTR0.04−4.7233117_at0.013.14
LFNGcg20572537aBody0.04−3.8215270_at0.032.26
SMARCA1cg10076009bBody0.05−3.7215294_s_at0.032.29
PARVAcg15123662bBody0.02−3.4235279_at0.042.31
PDZD2cg22461201bTSS15000.01−3.2209493_at0.042.70
EXOC4cg25467879bBody0.02−3.2240528_s_at0.012.32
SIPA1L1cg02058870b5′UTR0.04−2.6202254_at0.034.60
ACSF3cg05521982bTSS15000.02−2.4227464_at0.021.79
GNG7cg08481112b5′UTR0.01−2.0228831_s_at0.042.01
cg19382697a5′UTR −1.1
KCNT1cg03358588bBody0.051.51569462_x_at0.01−2.61
cg01841415bBody0.032.0
cg13463516bBody0.023.2
OSBPL1Acg27638913bBody0.043.31554646_at0.04−1.87
PPP2R2Ccg23195028bBody0.013.3223573_s_at0.01−4.64
JPH3cg04769798aBody0.053.3229294_at0.01−2.64
GOLGA3cg23755933a3′UTR0.033.31554987_at0.04−1.54
TTLL9cg09044785b5′UTR0.053.7234337_at0.02−1.41
BAI1cg25473866bBody0.012.1206083_at−1.68
cg21934273aBody0.013.8
SAMD3cg09345868b5′UTR0.014.31553876_at0.04−1.70
PPP2R1Bcg09085632aTSS2000.045.6222351_at0.02−2.33
  1. Data are presented as mean ± SD
  2. Methylation difference:  % methylation (Ob) −  % Methylation (L); values for  % Methylation of groups are located in Additional file 4: Table S4. Significant probes from global DNA methylation analysis and global gene expression analysis were overlaid for matching genes; Probeset ID represents a single gene that may contain multiple methylation (CpG) sites. The top hypo- and hypermethylated probes are presented with corresponding gene probe
  3. aInfinium I probe design
  4. bInfinium II probe design. Gene names are located in Additional file 4: Table S4