Table 4 Effects of chloroquine vs. placebo over 24 months (off either, i.e. washout, months 12–24)

110.4 ± 10.5

112.5 ± 12.6

112.6 ± 13.6

108.9 ± 11.8

110.4 ± 13.8

109.8 ± 12.4

102.9 ± 16.7

102.9 ± 16.7

103.1 ± 19.2

99.7 ± 18.5

98.7 ± 18.5

99.2 ± 17.8

5.48 ± 0.53

5.36 ± 0.55

5.30 ± 0.51

5.52 ± 0.64

5.52 ± 0.62

5.51 ± 0.71

16.32 ± 2.46

15.94 ± 2.24

16.17 ± 2.58

16.54 ± 3.49

16.87 ± 3.29

16.43 ± 3.34

1202 ± 681

1118 ± 542

1143 ± 603

1003 ± 524

1054 ± 588

995 ± 570

7.46 ± 2.33

7.23 ± 2.10

7.16 ± 2.20

6.49 ± 1.80

6.69 ± 2.06

6.46 ± 2.00

3.89 ± 2.23

3.85 ± 2.21

3.57 ± 2.12

3.54 ± 2.03

3.64 ± 2.08

3.30 ± 2.23

2.89 ± 1.72

2.88 ± 1.55

3.13 ± 2.31

3.21 ± 1.89

3.07 ± 1.64

3.50 ± 2.14

1.40 ± 1.75

1.17 ± 0.87

1.24 ± 0.87

1.05 ± 0.77

1.03 ± 0.67

1.09 ± 0.88

174.0 ± 63.5

152.3 ± 60.3

126.8 ± 43.3

168.0 ± 60.6

138.7 ± 46.7

119.8 ± 36.2

68 ± 14

67 ± 15

66 ± 15

66 ± 16

65 ± 17

65 ± 17

26 ± 16

26 ± 19

26 ± 15

25 ± 12

27 ± 16

23 ± 9

6.7 ± 1.8

6.3 ± 1.6

6.0 ± 1.5

6.5 ± 1.7

6.3 ± 1.8

6.1 ± 1.9

13.6 ± 1.1

13.3 ± 1.1

13.2 ± 1.2

13.8 ± 0.8

13.5 ± 0.9

13.5 ± 0.9