Ā | HC | NAFLD | CHB | CHB with NAFLD | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
HOMA-IR ā¤ā2.7 | HOMA-IR >ā2.7 | P | HOMA-IR ā¤ā2.7 | HOMA-IR >ā2.7 | P | HOMA-IR ā¤ā2.7 | HOMA-IR >ā2.7 | P | HOMA-IR ā¤ā2.7 | HOMA-IR >ā2.7 | P | |
(Nā=ā648) | (Nā=ā19) | (Nā=ā554) | (Nā=ā324) | (Nā=ā855) | (Nā=ā115) | (Nā=ā148) | (Nā=ā105) | |||||
Male (nĀ %) | 430 (66) | 10 (53) | 0.017 | 406 (73) | 212 (65) | 0.318 | 569 (67) | 82 (71) | 0.361 | 111 (75) | 81 (77) | 0.808 |
Age (year) | 39.4 (9.4) | 43.6 (10.3) | 0.182 | 41.4 (11.2) | 39.6 (12.2) | 0.019 | 39.9 (11.7) | 39.4 (10.3) | 0.625 | 41.2 (10.4) | 40.7 (11.1) | 0.53 |
BMI (kg/m2) | 21.68 (2.39) | 23.90 (3.00) | <ā0.001 | 25.67 (3.12) | 28.01 (4.22) | <ā0.001 | 21.87 (3.01) | 24.21 (3.14) | <ā0.001 | 25.03 (3.03) | 27.36 (4.16) | <ā0.001 |
Waistāhip ratio | 0.80 (0.06) | 0.79 (0.03) | 0.001 | 0.89 (0.04) | 0.90 (0.05) | 0.557 | 0.84 (0.07) | 0.87 (0.06) | <ā0.001 | 0.88 (0.05) | 0.90 (0.05) | 0.004 |
SBP (mmHg) | 116.2 (11.8) | 124.8 (11.6) | <ā0.001 | 126.8 (13.7) | 130.7 (14.7) | 0.001 | 124.2 (10.1) | 127.2 (14.0) | 0.004 | 128.7 (10.9) | 130.5 (12.0) | 0.286 |
DBP (mmHg) | 72.0 (9.4) | 74.4 (10.7) | <ā0.001 | 80.9 (10.1) | 84.4 (11.0) | 0.241 | 81.1 (7.2) | 85.1 (9.7) | <ā0.001 | 85.2 (9.4) | 86.7 (12.5) | 0.078 |
CHOL (mmol/L) | 4.69 (0.63) | 5.18 (0.77) | 0.023 | 5.40 (1.04) | 5.57 (1.16) | 0.001 | 4.90 (1.08) | 5.03 (1.01) | 0.206 | 5.04 (1.04) | 5.53 (1.03) | <ā0.001 |
TG (mmol/L) | 0.99 (0.48) | 1.33 (0.65) | 0.093 | 2.40 (2.10) | 2.69 (2.96) | 0.003 | 1.24 (0.72) | 1.56 (1.02) | <ā0.001 | 1.63 (1.04) | 1.89 (1.53) | 0.114 |
HDL-C (mmol/L) | 1.36 (0.24) | 1.31 (0.25) | 0.001 | 1.17 (0.35) | 1.09 (0.31) | 0.323 | 1.35 (0.39) | 1.24 (0.39) | 0.002 | 1.17 (0.28) | 1.17 (0.50) | 0.880 |
LDL-C (mmol/L) | 2.87 (0.68) | 3.43 (0.78) | 0.051 | 3.28 (0.88) | 3.40 (0.93) | <ā0.001 | 3.05 (0.83) | 3.16 (0.87) | 0.161 | 3.20 (0.85) | 3.64 (0.87) | <ā0.001 |
FBG (mmol/L) | 4.77 (0.44) | 5.12 (0.51) | <ā0.001 | 5.12 (0.81) | 5.79 (1.47) | 0.001 | 4.73 (0.62) | 5.56 (0.97) | <ā0.001 | 4.83 (0.65) | 5.88 (1.70) | <ā0.001 |
FINS (Ī¼U/mL) | 5.90 (2.02) | 17.86 (11.72) | <ā0.001 | 7.96 (2.58) | 16.98 (9.34) | <ā0.001 | 5.96 (2.61) | 16.93 (6.00) | <ā0.001 | 7.41 (2.47) | 18.37 (8.51) | <ā0.001 |
HOMA-IR | 1.26 (0.47) | 4.04 (2.71) | <ā0.001 | 1.79 (0.57) | 4.31 (2.72) | <ā0.001 | 1.26 (0.59) | 4.23 (2.00) | <ā0.001 | 1.59 (0.56) | 4.82 (3.04) | <ā0.001 |
UA (Ī¼mol/L) | 309.4 (88.8) | 319.6 (81.2) | <ā0.001 | 394.2 (99.0) | 418.9 (106.2) | 0.593 | 337.2 (92.2) | 351.9 (89.0) | 0.103 | 393.1 (99.2) | 413.0 (83.3) | 0.089 |
ALT (U/L) | 20.0 (10.1) | 31.0 (17.8) | <ā0.001 | 45.2 (39.2) | 61.9 (49.7) | <ā0.001 | 53.5 (91.1) | 64.2 (88.3) | 0.252 | 51.9 (55.0) | 77.4 (76.2) | 0.002 |
AST (U/L) | 23.3 (5.9) | 27.4 (6.1) | 0.004 | 35.0 (26.9) | 40.2 (24.4) | 0.006 | 44.0 (77.2) | 43.9 (48.1) | 0.999 | 40.4 (45.3) | 50.9 (40.2) | 0.036 |
ALB (g/L) | 46.49 (0.17) | 46.54 (0.11) | 0.207 | 46.06 (2.50) | 45.81 (3.26) | 0.221 | 44.83 (3.98) | 44.96 (4.93) | 0.765 | 45.15 (3.83) | 45.21 (3.84) | 0.867 |
TB (Ī¼mol/L) | 13.59 (0.19) | 13.53 (0.14) | 0.225 | 14.62 (4.90) | 14.19 (5.31) | 0.123 | 15.28 (6.75) | 14.48 (6.83) | 0.233 | 15.44 (7.17) | 14.34 (4.46) | 0.163 |