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TableĀ 2 Characteristics of all subjects with and without insulin resistance

From: Insulin resistance exhibits varied metabolic abnormalities in nonalcoholic fatty liver disease, chronic hepatitis B and the combination of the two: a cross-sectional study

Ā 

HC

NAFLD

CHB

CHB with NAFLD

HOMA-IR ā‰¤ā€‰2.7

HOMA-IR >ā€‰2.7

P

HOMA-IR ā‰¤ā€‰2.7

HOMA-IR >ā€‰2.7

P

HOMA-IR ā‰¤ā€‰2.7

HOMA-IR >ā€‰2.7

P

HOMA-IR ā‰¤ā€‰2.7

HOMA-IR >ā€‰2.7

P

(Nā€‰=ā€‰648)

(Nā€‰=ā€‰19)

(Nā€‰=ā€‰554)

(Nā€‰=ā€‰324)

(Nā€‰=ā€‰855)

(Nā€‰=ā€‰115)

(Nā€‰=ā€‰148)

(Nā€‰=ā€‰105)

Male (nĀ %)

430 (66)

10 (53)

0.017

406 (73)

212 (65)

0.318

569 (67)

82 (71)

0.361

111 (75)

81 (77)

0.808

Age (year)

39.4 (9.4)

43.6 (10.3)

0.182

41.4 (11.2)

39.6 (12.2)

0.019

39.9 (11.7)

39.4 (10.3)

0.625

41.2 (10.4)

40.7 (11.1)

0.53

BMI (kg/m2)

21.68 (2.39)

23.90 (3.00)

<ā€‰0.001

25.67 (3.12)

28.01 (4.22)

<ā€‰0.001

21.87 (3.01)

24.21 (3.14)

<ā€‰0.001

25.03 (3.03)

27.36 (4.16)

<ā€‰0.001

Waistā€“hip ratio

0.80 (0.06)

0.79 (0.03)

0.001

0.89 (0.04)

0.90 (0.05)

0.557

0.84 (0.07)

0.87 (0.06)

<ā€‰0.001

0.88 (0.05)

0.90 (0.05)

0.004

SBP (mmHg)

116.2 (11.8)

124.8 (11.6)

<ā€‰0.001

126.8 (13.7)

130.7 (14.7)

0.001

124.2 (10.1)

127.2 (14.0)

0.004

128.7 (10.9)

130.5 (12.0)

0.286

DBP (mmHg)

72.0 (9.4)

74.4 (10.7)

<ā€‰0.001

80.9 (10.1)

84.4 (11.0)

0.241

81.1 (7.2)

85.1 (9.7)

<ā€‰0.001

85.2 (9.4)

86.7 (12.5)

0.078

CHOL (mmol/L)

4.69 (0.63)

5.18 (0.77)

0.023

5.40 (1.04)

5.57 (1.16)

0.001

4.90 (1.08)

5.03 (1.01)

0.206

5.04 (1.04)

5.53 (1.03)

<ā€‰0.001

TG (mmol/L)

0.99 (0.48)

1.33 (0.65)

0.093

2.40 (2.10)

2.69 (2.96)

0.003

1.24 (0.72)

1.56 (1.02)

<ā€‰0.001

1.63 (1.04)

1.89 (1.53)

0.114

HDL-C (mmol/L)

1.36 (0.24)

1.31 (0.25)

0.001

1.17 (0.35)

1.09 (0.31)

0.323

1.35 (0.39)

1.24 (0.39)

0.002

1.17 (0.28)

1.17 (0.50)

0.880

LDL-C (mmol/L)

2.87 (0.68)

3.43 (0.78)

0.051

3.28 (0.88)

3.40 (0.93)

<ā€‰0.001

3.05 (0.83)

3.16 (0.87)

0.161

3.20 (0.85)

3.64 (0.87)

<ā€‰0.001

FBG (mmol/L)

4.77 (0.44)

5.12 (0.51)

<ā€‰0.001

5.12 (0.81)

5.79 (1.47)

0.001

4.73 (0.62)

5.56 (0.97)

<ā€‰0.001

4.83 (0.65)

5.88 (1.70)

<ā€‰0.001

FINS (Ī¼U/mL)

5.90 (2.02)

17.86 (11.72)

<ā€‰0.001

7.96 (2.58)

16.98 (9.34)

<ā€‰0.001

5.96 (2.61)

16.93 (6.00)

<ā€‰0.001

7.41 (2.47)

18.37 (8.51)

<ā€‰0.001

HOMA-IR

1.26 (0.47)

4.04 (2.71)

<ā€‰0.001

1.79 (0.57)

4.31 (2.72)

<ā€‰0.001

1.26 (0.59)

4.23 (2.00)

<ā€‰0.001

1.59 (0.56)

4.82 (3.04)

<ā€‰0.001

UA (Ī¼mol/L)

309.4 (88.8)

319.6 (81.2)

<ā€‰0.001

394.2 (99.0)

418.9 (106.2)

0.593

337.2 (92.2)

351.9 (89.0)

0.103

393.1 (99.2)

413.0 (83.3)

0.089

ALT (U/L)

20.0 (10.1)

31.0 (17.8)

<ā€‰0.001

45.2 (39.2)

61.9 (49.7)

<ā€‰0.001

53.5 (91.1)

64.2 (88.3)

0.252

51.9 (55.0)

77.4 (76.2)

0.002

AST (U/L)

23.3 (5.9)

27.4 (6.1)

0.004

35.0 (26.9)

40.2 (24.4)

0.006

44.0 (77.2)

43.9 (48.1)

0.999

40.4 (45.3)

50.9 (40.2)

0.036

ALB (g/L)

46.49 (0.17)

46.54 (0.11)

0.207

46.06 (2.50)

45.81 (3.26)

0.221

44.83 (3.98)

44.96 (4.93)

0.765

45.15 (3.83)

45.21 (3.84)

0.867

TB (Ī¼mol/L)

13.59 (0.19)

13.53 (0.14)

0.225

14.62 (4.90)

14.19 (5.31)

0.123

15.28 (6.75)

14.48 (6.83)

0.233

15.44 (7.17)

14.34 (4.46)

0.163

  1. Data are expressed as n (%) and mean (standard deviation)
  2. HC: health control; NAFLD: nonalcoholic fatty liver disease; CHB: chronic hepatitis B; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; CHOL: total cholesterol; TG: triglycerides; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; UA: uric acid; ALB: albumin; TB: total bilirubin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; FBG: fasting blood glucose; FINS: serum insulin