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TableĀ 1 Baseline characteristics of all patients

From: Insulin resistance exhibits varied metabolic abnormalities in nonalcoholic fatty liver disease, chronic hepatitis B and the combination of the two: a cross-sectional study

Ā 

ALL

HC

CHB

NAFLD

CHB with NAFLD

(Nā€‰=ā€‰2768)

(Nā€‰=ā€‰667)

(Nā€‰=ā€‰970)

(Nā€‰=ā€‰878)

(Nā€‰=ā€‰253)

Gender (male)

1901 (69%)

440 (66%)

651 (67%)

NSaā€”

618 (70%)

NSab

192 (76%)

*ab, NSc

Age (year)

40.1 (10.9)

39.3 (9.2)

39.8 (11.7)

NSa

41.1 (12.0)

NSab

41.0 (10.2)

NSac, *b

BMI (kg/m2)

23.8 (3.9)

21.8 (2.4)

22.2 (3.1)

**a

26.5 (3.7)

**ab

26.0 (3.7)

**ab, *c

Waistā€“hip ratio

0.85 (0.07)

0.80 (0.06)

0.84 (0.07)

**a

0.89 (0.04)

**ab

0.89 (0.05)

**ab, NSc

SBP (mmHg)

124.2 (13.1)

116.2 (12.1)

124.8 (10.1)

**a

127.7 (14.7)

**ab

130.0 (10.8)

**ab, *c

DBP (mmHg)

79.8 (9.9)

72.1 (9.2)

82.3 (8.1)

**a

82.4 (9.9)

**a, *b

86.0 (11.1)

**ab

CHOL (mmol/L)

5.1 (1.0)

4.7 (0.6)

4.9 (1.1)

**a

5.5 (1.1)

**ab

5.2 (1.1)

**ab, *c

TG (mmol/L)

1.6 (1.7)

1.0 (0.5)

1.3 (0.8)

**a

2.5 (2.5)

**ab

1.7 (1.3)

**ab

HDL-C (mmol/L)

1.3 (0.4)

1.4 (0.2)

1.3 (0.4)

NSa

1.1 (0.3)

**ab

1.2 (0.4)

**ab, NSc

LDL-C (mmol/L)

3.1 (0.9)

2.9 (0.7)

3.1 (0.8)

**a

3.3 (0.9)

**ab

3.4 (0.9)

**ab, NSc

FBG (mmol/L)

5.0 (0.9)

4.8 (0.4)

4.8 (0.7)

NSa

5.4 (1.2)

**ab

5.3 (1.3)

**ab, *c

FINS (Ī¼U/mL)

8.7 (6.3)

6.2 (3.4)

7.3 (4.8)

*a

11.3 (7.4)

**ab

12.0 (7.9)

**ab, NSc

HOMA-IR

2.0 (1.8)

1.3 (0.8)

1.6 (1.3)

*a

2.7 (2.1)

**ab

2.9 (2.6)

**ab, NSc

UA (Ī¼mol/L)

358.2 (102.4)

309.1 (89.0)

339.0 (92.2)

**a

402.8 (102.2)

**ab

401.9 (93.2)

**ab, NSc

ALT (U/L)

45.9 (63.5)

20.1 (10.9)

55.1 (90.9)

**a

51.4 (44.4)

**ab

61.5 (64.5)

**ab,*c

AST (U/L)

37.1 (49.0)

24.4 (6.0)

44.2 (75.4)

**a

37.3 (26.2)

**a, *b

44.0 (43.1)

**a, *bc

ALB (g/L)

45.6 (3.2)

46.5 (0.2)

44.9 (4.1)

**a

45.97 (2.8)

**ab

45.2 (3.8)

**ac, *b

TB (Ī¼mol/L)

14.6 (5.3)

13.6 (0.2)

15.2 (6.8)

*a

14.46 (5.1)

**a, NSb

14.5 (6.2)

*a, NSbc

  1. HC: health control; NAFLD: nonalcoholic fatty liver disease; CHB: chronic hepatitis B; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; CHOL: total cholesterol; TG: triglycerides; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; UA: uric acid; ALB: albumin; TB: total bilirubin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; FBG: fasting blood glucose; FINS: serum insulin
  2. Data are n (%) and mean (Standard deviation). P values were for the ANOVA analysis across the groups, * Pā€‰<ā€‰0.05, ** Pā€‰<ā€‰0.001
  3. ā€”aā€”compared with HC group, bā€”compared with CHB group, cā€”compared with NAFLD group, NSā€” non significant