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Table 2 Effects of AIT intervention on serum biomarkers

From: An attempt to reverse cardiac lipotoxicity by aerobic interval training in a high-fat diet- and streptozotocin-induced type 2 diabetes rat model

 

CON

DCM

AIT

N

9

10

9

FBG (mmol/L)

8.26 ± 1.48

25.22 ± 4.65##

13.70 ± 3.43ƗƗ,*

Insulin (pg/L)

2.55 ± 0.18

3.02 ± 0.29#

3.24 ± 0.37*

HOMA-IR

0.93 ± 0.15

3.35 ± 0.44##

2.01 ± 0.68ƗƗ,*

HOMA-β

11.88 ± 4.83

2.97 ± 1.06##

6.93 ± 2.16ƗƗ,*

OGTTAUC (mmol/L)

12.29 ± 0.85

52.73 ± 4.57##

34.87 ± 11.71ƗƗ,*

TG (mmol/L)

0.76 ± 0.39

1.62 ± 0.95##

0.39 ± 0.12*

TC (mmol/L)

2.19 ± 0.30

2.80 ± 0.54

2.52 ± 0.34

HDL-C (mmol/L)

1.84 ± 0.07

1.13 ± 0.51##

1.82 ± 0.07*

LDL-C (mmol/L)

0.42 ± 0.03

1.49 ± 0.92##

0.66 ± 0.19*

  1. Data are expressed as the mean ± SD
  2. FBG fasting blood glucose, HOMA-IR insulin resistance index, HOMA-β β cell function index, OGTTAUC oral glucose tolerance test area under the curve, TG triacylglycerol, TC total cholesterol, HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol
  3. #P < 0.05 as DCM group vs. CON group, ##P < 0.01 as DCM group vs. CON group; ƗƗP < 0.01 as AIT group vs. CON group; * P < 0.05 as AIT group vs. DCM group (ANOVA)