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Table 2 Effects of AIT intervention on serum biomarkers

From: An attempt to reverse cardiac lipotoxicity by aerobic interval training in a high-fat diet- and streptozotocin-induced type 2 diabetes rat model

  CON DCM AIT
N 9 10 9
FBG (mmol/L) 8.26 ± 1.48 25.22 ± 4.65## 13.70 ± 3.43ƗƗ,*
Insulin (pg/L) 2.55 ± 0.18 3.02 ± 0.29# 3.24 ± 0.37*
HOMA-IR 0.93 ± 0.15 3.35 ± 0.44## 2.01 ± 0.68ƗƗ,*
HOMA-β 11.88 ± 4.83 2.97 ± 1.06## 6.93 ± 2.16ƗƗ,*
OGTTAUC (mmol/L) 12.29 ± 0.85 52.73 ± 4.57## 34.87 ± 11.71ƗƗ,*
TG (mmol/L) 0.76 ± 0.39 1.62 ± 0.95## 0.39 ± 0.12*
TC (mmol/L) 2.19 ± 0.30 2.80 ± 0.54 2.52 ± 0.34
HDL-C (mmol/L) 1.84 ± 0.07 1.13 ± 0.51## 1.82 ± 0.07*
LDL-C (mmol/L) 0.42 ± 0.03 1.49 ± 0.92## 0.66 ± 0.19*
  1. Data are expressed as the mean ± SD
  2. FBG fasting blood glucose, HOMA-IR insulin resistance index, HOMA-β β cell function index, OGTTAUC oral glucose tolerance test area under the curve, TG triacylglycerol, TC total cholesterol, HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol
  3. #P < 0.05 as DCM group vs. CON group, ##P < 0.01 as DCM group vs. CON group; ƗƗP < 0.01 as AIT group vs. CON group; * P < 0.05 as AIT group vs. DCM group (ANOVA)