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Fig. 3 | Diabetology & Metabolic Syndrome

Fig. 3

From: Stem cells from human exfoliated deciduous teeth ameliorate type II diabetic mellitus in Goto-Kakizaki rats

Fig. 3

Infusion of SHED promotes restoration of pancreatic islets in T2DM rats. a Pancreas histology was studied via HE staining, observed under light microscopy and focused on islet structures. b Pancreatic islets were characterized by immunofluorescence according to the presence and distribution of insulin-producing (green) and glucagon-producing (red) cells in four groups of rats at 8 weeks after infusion. Images were composite overlays of the individually stained nuclei, insulin and glucagon. SHED and BMSCs injection significantly improved abnormalities in pancreatic islets. c The proportion of the irregular islets and the proportion of β-cells in 4 group. ***P<0.001

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