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Table 1 Baseline characteristics

From: Reduced plasma albumin predicts type 2 diabetes and is associated with greater adipose tissue macrophage content and activation

 

Adipose tissue

Cross-sectional analysis

Prospective analysis

Non-progressors

Progressors

n

51

422

277

102

Male, n (%)

33 (65)

243 (58)

171 (62)

43 (42)c

Age (years)a

31 (23, 39)

27 (23, 32)

26 (22, 31)

28 (24, 32)d

Full heritage, n (%)

37 (73)

345 (82)

217 (78)

92 (90)e

Body weight (kg)b

94 (24)

94 (23)

91 (21)

102 (22)f

BMI (kg/m2)b

33 (8)

34 (8)

33 (7)

38 (7)f

Body fat (%)b

31 (8)

33 (8)

31 (8)

36 (7)f

FPG (mmol/l)b

4.8 (0.5)

5.0 (0.6)

4.9 (0.6)

5.2 (0.6)f

2 h-PG (mmol/l)b

6.5 (1.8)

6.9 (1.8)

6.5 (1.6)

7.9 (1.8)f

NGR/IGR

33/18

265/157

198/79

41/61

Fasting insulin—OGTT (pmol/L)a

155 (89, 272)

153 (76, 271)

139 (69, 236)

236 (132, 382)f

M (mg kg −1EMBS  min−1)a

2.80 (2.41, 3.86)

2.29 (1.99, 2.87)

2.48 (2.11, 3.19)

2.03 (1.86, 2.64)f

AIR (pmol/l)a

1347 (860, 2309)

1403 (917, 2132)

1535 (1000, 2215)

1264 (785, 1833)d

EGP—basal (mg kg −1EMBS  min−1)b

1.95 (0.35)

2.45 (0.40)

1.90 (0.24)

1.91 (0.26)

EGP—insulin (mg kg −1EMBS  min−1)a

0.27 (0, 0.60)

0.25 (0, 0.58)

0.19 (0, 0.56)

0.39 (0.15, 0.70)f

Albumin (g/l)b

39.6 (4.2)

39.8 (4.2)

40.2 (4.3)

38.7 (3.6)f

  1. NGR normal glucose regulation, IGR impaired glucose regulation, EMBS estimated metabolic body size = fat-free mass + 17.7, EGP endogenous glucose production
  2. aData reported as the median (IQR; 25th to 75th percentile)
  3. bData reported as the mean (SD)
  4. c < 0.001
  5. d < 0.05
  6. e < 0.01
  7. f < 0.0001