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Table 1 Baseline characteristics

From: Reduced plasma albumin predicts type 2 diabetes and is associated with greater adipose tissue macrophage content and activation

  Adipose tissue Cross-sectional analysis Prospective analysis
Non-progressors Progressors
n 51 422 277 102
Male, n (%) 33 (65) 243 (58) 171 (62) 43 (42)c
Age (years)a 31 (23, 39) 27 (23, 32) 26 (22, 31) 28 (24, 32)d
Full heritage, n (%) 37 (73) 345 (82) 217 (78) 92 (90)e
Body weight (kg)b 94 (24) 94 (23) 91 (21) 102 (22)f
BMI (kg/m2)b 33 (8) 34 (8) 33 (7) 38 (7)f
Body fat (%)b 31 (8) 33 (8) 31 (8) 36 (7)f
FPG (mmol/l)b 4.8 (0.5) 5.0 (0.6) 4.9 (0.6) 5.2 (0.6)f
2 h-PG (mmol/l)b 6.5 (1.8) 6.9 (1.8) 6.5 (1.6) 7.9 (1.8)f
NGR/IGR 33/18 265/157 198/79 41/61
Fasting insulin—OGTT (pmol/L)a 155 (89, 272) 153 (76, 271) 139 (69, 236) 236 (132, 382)f
M (mg kg EMBS −1  min−1)a 2.80 (2.41, 3.86) 2.29 (1.99, 2.87) 2.48 (2.11, 3.19) 2.03 (1.86, 2.64)f
AIR (pmol/l)a 1347 (860, 2309) 1403 (917, 2132) 1535 (1000, 2215) 1264 (785, 1833)d
EGP—basal (mg kg EMBS −1  min−1)b 1.95 (0.35) 2.45 (0.40) 1.90 (0.24) 1.91 (0.26)
EGP—insulin (mg kg EMBS −1  min−1)a 0.27 (0, 0.60) 0.25 (0, 0.58) 0.19 (0, 0.56) 0.39 (0.15, 0.70)f
Albumin (g/l)b 39.6 (4.2) 39.8 (4.2) 40.2 (4.3) 38.7 (3.6)f
  1. NGR normal glucose regulation, IGR impaired glucose regulation, EMBS estimated metabolic body size = fat-free mass + 17.7, EGP endogenous glucose production
  2. aData reported as the median (IQR; 25th to 75th percentile)
  3. bData reported as the mean (SD)
  4. c < 0.001
  5. d < 0.05
  6. e < 0.01
  7. f < 0.0001