Fig. 8

The effects of 6-shogaol on renal Nrf2 levels in type 2 diabetic mice. Renal tissues from different groups were collected at the indicated times for measuring Nrf-2 expression at the mRNA levels with RT-PCR, respectively. Data are presented as mean ± SEM. n = 4 in diabetic group and n = 3 in each other group. *p, 0.05 vs. the corresponding control group; ^#p, 0.05 vs. the corresponding STZ group. Con, control mice; Sho 10 mg/kg, control mice treated with 6-shogaol at 10 mg/kg; STZ, STZ induced diabetic mice without 6-shogaol treatment; STZ + Sho 5 mg/kg, STZ induced diabetic mice with 6-shogaol at 5 mg/kg; STZ + Sho 10 mg/kg, STZ induced diabetic mice with 6-shogaol at 10 mg/kg