Skip to main content

Table 3 Association between changes in log[hsCRP] and various parameters coefficients

From: Anti-inflammatory effects of empagliflozin in patients with type 2 diabetes and insulin resistance

  Estimate Std. error t value P
∆ACR (mg/gCr) 0.0006272 0.0003121 2.01 0.0697
∆BMI − 0.004537 0.01105 − 0.411 0.6892
∆DBP (mmHg) − 0.002671 0.002109 − 1.266 0.2316
∆eGFR (ml/min/1.73m2) 0.0002273 0.002345 0.097 0.9246
∆γGTP (IU/L) − 0.001513 0.001401 − 1.08 0.3031
∆AST (IU/L) 0.003259 0.001935 1.684 0.1203
∆ALT (IU/L) − 0.003582 0.00151 − 2.372 0.037*
∆HbA1c (%) 0.04275 0.02592 1.65 0.1273
∆HDL-C (mg/dL) − 0.002794 0.001159 − 2.411 0.0346*
∆HOMA-IR 0.06453 0.0254 2.541 0.0274*
∆LDL (mg/dL) 0.0008015 0.0008732 0.918 0.3784
∆RLPC (mg/dL) 0.06442 0.02548 2.528 0.0281*
∆SBP (mmHg) − 0.002882 0.00124 − 2.324 0.0403*
∆TG (mg/dL) 0.000000518 0.0003293 0.002 0.9988
  1. R2 = 0.9855, p-value = 4.709 × 10−8
  2. Multiple linear regression analysis was used to test the association between change in log[hsCRP] and changes in various parameters across 12 months in EMPA group
  3. hsCRP high sensitivity C-reactive protein, ACR albumin-to-creatinine ratio, BMI body mass index, eGFR estimated glomerular filtration rate, GTP, gamma-glutamyl transpeptidase, AST aspartate aminotransferase, ALT alanine aminotransferase, HbA1c hemoglobin A1c, HDL-C HDL cholesterol, LDL-C LDL cholesterol, TG triglyceride, RLP-C remnant-like particle cholesterol, SBP systolic blood pressure, DBP diastolic blood pressure
  4. *p < 0.05