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Table 2 Association of leptin, E-selectin and sub fractions of lipoprotein with neck circumference according to sex, considering the entire sample and individuals at low cardiovascular risk

From: Neck circumference is associated with non-traditional cardiovascular risk factors in individuals at low-to-moderate cardiovascular risk: cross-sectional analysis of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

  Leptin E-selectin Small-dense LDL-C HDL2-C
β 95% CI p β 95% CI p β 95% CI p β 95% CI p
Entire sample
 Men
  Neck circumference 0.155 0.069 to 0.242 < 0.001 0.105 0.032 to 0.177 0.005 1.866 0.641 to 3.091 0.003 − 0.519 − 0.773 to − 0.266 < 0.001
 Women
  Neck circumference 0.147 0.075 to 0.220 < 0.001 0.73 0.006 to 0.140 0.032 2.372 1.391 to 3.353 < 0.001 − 0.815 − 1.115 to − 0.515 < 0.001
Lower risk subsample
 Men
  Neck circumference 0.183 0.084 to 0.282 < 0.001 0.95 0.015 to 0.175 0.021 1.758 0.478 to 3.039 0.007 − 0.476 − 0.766 to − 0.186 0.001
 Women
  Neck circumference 0.152 0.075 to 0.229 < 0.001 0.068 − 0.004 to 0.140 0.066 1.620 0.597 to 2.643 0.002 − 0.685 − 1.013 to − 0.356 < 0.001
Higher risk subsample
 Men
  Neck circumference 0.001 − 0.103 to 0.103 0.995 0.074 − 0.033 to 0.181 0.173 − 2.520 − 6.299 to 1.260 0.187 0.165 − 0.273 to 0.640 0.454
 Women
  Neck circumference − 0.014 − 0.068 to 0.041 0.619 0.015 − 0.034 to 0.064 0.545 1.610 − 1.484 to 4.705 0.300 − 0.076 − 0.514 to 0.667 0.796
  1. Linear regression analysis. Adjusted for age. Lower risk subsample—individuals with up to 2 cardiovascular risk factors. Higher risk subsample—3 or more cardiovascular risk factors. Traditional cardiovascular risk factors: (1) waist circumference ≥ 102 cm for men or ≥ 88 cm for women; (2) systolic or diastolic blood pressure ≥ 130/85 mmHg or antihypertensive treatment; (3) fasting plasma glucose ≥ 100 mg/dL and < 126 mg/dL in the absence of antidiabetic agents; (4) triglyceride ≥ 150 mg/dL, or specific treatment; (5) HDL-cholesterol < 40 mg/dL for men and < 50 mg/dL for women, or specific treatment