Diabetology & Metabolic Syndrome

Table 2 Association of leptin, E-selectin and sub fractions of lipoprotein with neck circumference according to sex, considering the entire sample and individuals at low cardiovascular risk

From: Neck circumference is associated with non-traditional cardiovascular risk factors in individuals at low-to-moderate cardiovascular risk: cross-sectional analysis of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

	Leptin			E-selectin			Small-dense LDL-C			HDL₂-C
	β	95% CI	p	β	95% CI	p	β	95% CI	p	β	95% CI	p
Entire sample
Men
Neck circumference	0.155	0.069 to 0.242	< 0.001	0.105	0.032 to 0.177	0.005	1.866	0.641 to 3.091	0.003	− 0.519	− 0.773 to − 0.266	< 0.001
Women
Neck circumference	0.147	0.075 to 0.220	< 0.001	0.73	0.006 to 0.140	0.032	2.372	1.391 to 3.353	< 0.001	− 0.815	− 1.115 to − 0.515	< 0.001
Lower risk subsample
Men
Neck circumference	0.183	0.084 to 0.282	< 0.001	0.95	0.015 to 0.175	0.021	1.758	0.478 to 3.039	0.007	− 0.476	− 0.766 to − 0.186	0.001
Women
Neck circumference	0.152	0.075 to 0.229	< 0.001	0.068	− 0.004 to 0.140	0.066	1.620	0.597 to 2.643	0.002	− 0.685	− 1.013 to − 0.356	< 0.001
Higher risk subsample
Men
Neck circumference	0.001	− 0.103 to 0.103	0.995	0.074	− 0.033 to 0.181	0.173	− 2.520	− 6.299 to 1.260	0.187	0.165	− 0.273 to 0.640	0.454
Women
Neck circumference	− 0.014	− 0.068 to 0.041	0.619	0.015	− 0.034 to 0.064	0.545	1.610	− 1.484 to 4.705	0.300	− 0.076	− 0.514 to 0.667	0.796

Linear regression analysis. Adjusted for age. Lower risk subsample—individuals with up to 2 cardiovascular risk factors. Higher risk subsample—3 or more cardiovascular risk factors. Traditional cardiovascular risk factors: (1) waist circumference ≥ 102 cm for men or ≥ 88 cm for women; (2) systolic or diastolic blood pressure ≥ 130/85 mmHg or antihypertensive treatment; (3) fasting plasma glucose ≥ 100 mg/dL and < 126 mg/dL in the absence of antidiabetic agents; (4) triglyceride ≥ 150 mg/dL, or specific treatment; (5) HDL-cholesterol < 40 mg/dL for men and < 50 mg/dL for women, or specific treatment

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ISSN: 1758-5996

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