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Table 2 Association of LIPC SNPs with adiposity status

From: LIPC variants as genetic determinants of adiposity status, visceral adiposity indicators, and triglyceride-glucose (TyG) index-related parameters mediated by serum triglyceride levels

SNPs Genotypes P* Adjusted P
MM Mm mm
rs2043085 CC CT TT   
BMI (kg/m2) 23.7 ± 3.3 24.4 ± 3.6 24.8 ± 3.4 0.002 0.024
WC (cm) 83.6 ± 9.2 85.1 ± 9.7 87.2 ± 9.8 2.8 × 10−4 3.4 × 10−3
HDL-C (mg/dL) 54.5 ± 14.1 55.9 ± 14.6 55.2 ± 14.2 0.001# 0.012
TG (mg/dL) 119.6 ± 65.4 144.8 ± 112.1 169.2 ± 175.7 2.8 × 10−6 3.4 × 10−5
rs1532085 GG GA AA   
BMI (kg/m2) 23.8 ± 3.3 24.5 ± 3.6 24.7 ± 3.4 0.006 0.072
WC (cm) 83.6 ± 9.3 85.2 ± 9.6 86.9 ± 9.9 0.001 0.012
HDL-C (mg/dL) 54.5 ± 14.0 55.8 ± 14.5 55.3 ± 14.5 0.001# 0.012
TG (mg/dL) 119.6 ± 65.5 144.6 ± 111.5 171.0 ± 179.8 2.2 × 10−6 2.6 × 10−5
rs1800588 CC CT TT   
BMI (kg/m2) 24.4 ± 3.5 24.4 ± 3.5 23.6 ± 3.4 0.432 1.0
WC (cm) 85.5 ± 9.8 85.2 ± 9.4 83.4 ± 9.8 0.631 1.0
HDL-C (mg/dL) 53.9 ± 13.1 55.7 ± 14.7 58.3 ± 16.1 0.001# 0.012
TG (mg/dL) 135.1 ± 96.1 147.9 ± 139.7 146.8 ± 105.8 0.001 0.012
  1. Abbreviations as in Table 1
  2. MM homozygosity of major allele, Mm heterozygosity, mm homozygosity of minor allele
  3. Adjusted P: the P value were shown with Bonferroni corrections, n = 12
  4. P*: adjusted for age, sex, current smoke, hypertension medicine, HDL-C
  5. #Adjusted for age, sex, current smoke, hypertension medicine, TG