Table 2 Association of LIPC SNPs with adiposity status
SNPs | Genotypes | P* | Adjusted P | ||
|---|---|---|---|---|---|
MM | Mm | mm | |||
rs2043085 | CC | CT | TT | Â | Â |
BMI (kg/m2) | 23.7 ± 3.3 | 24.4 ± 3.6 | 24.8 ± 3.4 | 0.002 | 0.024 |
WC (cm) | 83.6 ± 9.2 | 85.1 ± 9.7 | 87.2 ± 9.8 | 2.8 × 10−4 | 3.4 × 10−3 |
HDL-C (mg/dL) | 54.5 ± 14.1 | 55.9 ± 14.6 | 55.2 ± 14.2 | 0.001# | 0.012 |
TG (mg/dL) | 119.6 ± 65.4 | 144.8 ± 112.1 | 169.2 ± 175.7 | 2.8 × 10−6 | 3.4 × 10−5 |
rs1532085 | GG | GA | AA | Â | Â |
BMI (kg/m2) | 23.8 ± 3.3 | 24.5 ± 3.6 | 24.7 ± 3.4 | 0.006 | 0.072 |
WC (cm) | 83.6 ± 9.3 | 85.2 ± 9.6 | 86.9 ± 9.9 | 0.001 | 0.012 |
HDL-C (mg/dL) | 54.5 ± 14.0 | 55.8 ± 14.5 | 55.3 ± 14.5 | 0.001# | 0.012 |
TG (mg/dL) | 119.6 ± 65.5 | 144.6 ± 111.5 | 171.0 ± 179.8 | 2.2 × 10−6 | 2.6 × 10−5 |
rs1800588 | CC | CT | TT | Â | Â |
BMI (kg/m2) | 24.4 ± 3.5 | 24.4 ± 3.5 | 23.6 ± 3.4 | 0.432 | 1.0 |
WC (cm) | 85.5 ± 9.8 | 85.2 ± 9.4 | 83.4 ± 9.8 | 0.631 | 1.0 |
HDL-C (mg/dL) | 53.9 ± 13.1 | 55.7 ± 14.7 | 58.3 ± 16.1 | 0.001# | 0.012 |
TG (mg/dL) | 135.1 ± 96.1 | 147.9 ± 139.7 | 146.8 ± 105.8 | 0.001 | 0.012 |