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Table 1 Baseline characteristics of the subjects with type 2 diabetes at study enrollment

From: Twice-daily insulin degludec/insulin aspart effectively improved morning and evening glucose levels and quality of life in patients previously treated with premixed insulin: an observational study

Parameter

Patients (n = 22)

Age (years)

68.0 ± 9.9

Male, n (%)

15 (68)

BMI (kg/m2)

23.9 [22.8, 25.4]

Duration of diabetes (years)

18.6 ± 9.2

Duration of insulin therapy (years)

9.2 ± 5.9

HbA1c (%)

7.7 ± 0.6

Fasting plasma glucose (mg/dL)

145.2 ± 24.3

Fasting serum C-peptide (ng/mL)

1.18 [0.85, 1.58]

eGFR (mL/min/1.73 m2)

61.8 ± 15.0

Diabetic complications, n (%)

 Retinopathy

5 (23)

 Nephropathy

7 (32)

 Neuropathy

8 (36)

Prior premixed insulin, n (%)

 BHI30

12 (55)

 BIAsp30

10 (45)

Oral antidiabetic agents, n (%)

 Sulfonylurea

1 (5)

 Metformin

4 (18)

 αGI

3 (14)

 DPP-4 inhibitor

10 (46)

 SGLT-2 inhibitor

1 (5)

Statins, n (%)

13 (59)

  1. Data are presented as means ± SD, median and interquartile ranges, or n (%)
  2. BMI body mass index, HbA1c glycated hemoglobin, eGFR estimated glomerular filtration rate, BHI30 human insulin 30%/neutral protamine Hagedorn insulin 70%, BIAsp30 insulin aspart 30%/protaminated insulin aspart 70%, αGI α-glucosidase inhibitor, DPP-4 dipeptidyl peptidase-4, SGLT-2 sodium glucose cotransporter-2