Fig. 3
From: Coenzyme Q10 suppresses apoptosis of mouse pancreatic β-cell line MIN6
CoQ10 prevents early events of apoptosis induced by STS treatment. Control, MIN6 cells cultured in regular medium; STS, cells exposed to STS (0.5 µM for 6 h); CoQ10, cells pretreated with CoQ10 (30 µM for 4 h) and then exposed to STS (0.5 µM for 6 h); Z-VAD, cells pretreated with Z-VAD-FMK (30 µM for 1 h) and then exposed to STS (0.5 µM for 6 h). Annexin-V-positive cells indicate exposure of PS at the cell surface, the early stage of apoptosis (green). Cells treated with methanol were PI positive (scale bar is 100 µm)