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Fig. 2 | Diabetology & Metabolic Syndrome

Fig. 2

From: Endoplasmic reticulum stress activation in adipose tissue induces metabolic syndrome in individuals with familial partial lipodystrophy of the Dunnigan type

Fig. 2

Oral Glucose Tolerance Test demonstrates the uncontrolled glycemic regulation and reduced insulin secretion. a Graph showing glucose levels during oGTT. The individuals in the FPLD group presented increased glucose levels in compared to control group. ***p < 0.005, ****p < 0.001. b Quantification of the insulin secretion during OTG. The FPLD group presented delayed insulin secretion compared to the control group *p < 0.05. c Area under the curve of oGTT graphs (plasma glucose and insulin). The AUC of glucose graph showed that individuals of FPLD group have higher AUC in compared to control group, demonstrating the uncontrolled glycemic; however no observed differences in insulin AUC. Student’s t test ****p < 0.001. d Evaluation of serum C-Reactive Protein levels. Student’s t test *p < 0.05. Control group (n = 13) and FPLD group (n = 14)

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