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Table 1 Clinical and biochemical characteristics of metabolically healthy non-obese (MHNO), metabolically healthy obese (MHO) and metabolically abnormal diabetic obese (MADO) subjects

From: Favourable metabolic profile sustains mitophagy and prevents metabolic abnormalities in metabolically healthy obese individuals

Variables MHNO (n = 20) MHO (n = 20) MADO (n = 20)
Age (years) 38.9 ± 7.2 41.5 ± 6.5 43.7 ± 10.8*
Gender (M:F) 12:8 11:9 11: 9
Wt (kg) 63.8 ± 7.7 72.2 ± 8.3* 73.1 ± 10.5*
BMI (kg/m2) 21.2 ± 1.6 28.5 ± 2.4*** 29.4 ± 3.5***
WC (cm) 81.0 ± 5.2 96.3 ± 7.7*** 98.6 ± 8.0***
Body Fat (%) 22.8 ± 6.2 33.6 ± 7.4* 35.0 ± 10.4***
Systolic BP (mm/Hg) 119.7 ± 12.1 122.7 ± 10.7 126.2 ± 15.2
Diastolic BP (mm/Hg) 80.7 ± 7.9 85.0 ± 6.1 81.8 ± 9.6
FPG (mmol/l) 5.1 ± 0.4 5.2 ± 0.7 8.6 ± 1.4***###
2hPG (mmol/l) 5.6 ± 1.3 6.8 ± 1.2 13.6 ± 2.7***###
HbA1C (%) 5.2 ± 0.2 5.3 ± 0.4 7.7 ± 0.5***###
FPI (μIU/ml) 9.7 ± 6.2 11.9 ± 5.1 13.6 ± 4.7
HOMA-IR 2.2 ± 1.4 2.4 ± 1.0 5.4 ± 2.5***###
HOMA-β % 119.5 ± 83.6 156.3 ± 81.1 54.2 ± 17.6***###
S. CHOL (mg/dl) 185.2 ± 39.1 180.4 ± 37.5 206.9 ± 44.8
S. LDL-C (mg/dl) 112.5 ± 27.9 108.1 ± 32.2 141.0 ± 36.7*##
S. TG (mg/dl) 134.2 ± 77.8 140.4 ± 70.2 152.2 ± 57.3
S. HDL-C (mg/dl) 44.2 ± 7.7 50.1 ± 16.7 44.2 ± 6.7
IL-6 (pg/ml) 6.9 ± 1.1 8.2 ± 2.2 15.2 ± 2.6**#
hsCRP (mg/dl) 0.7 ± 0.4 1.7 ± 1.2* 3.8 ± 2.3***#
  1. Data expressed as mean ± SD, * p < 0.05, ** p < 0.01, *** p < 0.001 vs. MHNO
  2. #p < 0.05, ## p < 0.01, ### p < 0.001 vs. MHO