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Table 1 Epidemiological, clinical, anthropometric and metabolic comparisons among the groups studied.

From: Hypermethylation in the promoter of the MTHFR gene is associated with diabetic complications and biochemical indicators

 

CONTROL (60)

DR (16)

p

DN (29)

p

Sex (M %)

26.6%

30.7%

0.4933

44%

0.0356*

Age (years)

57.5 ± 10

61 ± 9.1

0.3198

60 ± 6.8

0.2082

DM duration (years)

6 ± 2.1

7 ± 2.3

0.1092

7 ± 2.7

0.2000

Hypertention (%)

58.3%

69.2%

0.1089

92%

< 0.0001*

Dyslipidemia (%)

76.6%

69.2%

0.2391

96%

< 0.0001*

BMI (weight/height2)

28.7 ± 5.3

28.1 ± 4.1

0.5400

27.7 ± 4.5

0.4042

Abdominal circumference (centimeters)

104 ± 14.7

103 ± 11.3

0.7131

100 ± 10.7

0.2551

Glycemia (mg/dl)

152.5 ± 59.8

171 ± 62.5

0.6549

150 ± 53

0.8357

HbA1C (%)

7.8 ± 1.7

9 ± 2.6

0.0306**

8 ± 1.6

0.3880

Total cholesterol (mg/dl)

183.5 ± 42.9

189 ± 33.6

0.7293

193 ± 61.4

0.0244**

HDL cholesterol (mg/dl)

44 ± 10.6

44 ± 9.1

0.6037

41 ± 11.3

0.3853

LDL cholesterol (mg/dl)

105.5 ± 41.7

101.4 ± 49.6

0.9827

118 ± 61.3

0.1770

Triglycerides (mg/dl)

165.5 ± 93.2

177 ± 91.4

0.4578

177 ± 133.5

0.1252

Creatinine (mg/dl)

0.6 ± 0.3

0.8 ± 0.2

0.0255**

0.9 ± 0.3

0.0004**

Urinary albumin (mg/24 h)

5.2 ± 8.2

10.2 ± 8.1

0.2339

46 ± 158.1

0.0001**

CPR (mg/l)

2.4 ± 3.3

4.1 ± 3.3

0.1454

2 ± 3.3

0.8546

AGP (mg/dl)

80.5 ± 20.3

81 ± 29.8

0.6653

68 ± 31.4

0.0172**

TAC (%)

31.5 ± 30.2

44 ± 28.3

0.5072

13 ± 23.9

0.2116

MDA (µM)

3.7 ± 1

2.7 ± 1.5

0.1619

3.9 ± 1.2

0.5307

  1. All comparisons were performed in relation to the CONTROL
  2. * Significant difference—X 2
  3. ** Significant difference—Mann–Whitney U test