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Table 1 Epidemiological, clinical, anthropometric and metabolic comparisons among the groups studied.

From: Hypermethylation in the promoter of the MTHFR gene is associated with diabetic complications and biochemical indicators

  CONTROL (60) DR (16) p DN (29) p
Sex (M %) 26.6% 30.7% 0.4933 44% 0.0356*
Age (years) 57.5 ± 10 61 ± 9.1 0.3198 60 ± 6.8 0.2082
DM duration (years) 6 ± 2.1 7 ± 2.3 0.1092 7 ± 2.7 0.2000
Hypertention (%) 58.3% 69.2% 0.1089 92% < 0.0001*
Dyslipidemia (%) 76.6% 69.2% 0.2391 96% < 0.0001*
BMI (weight/height2) 28.7 ± 5.3 28.1 ± 4.1 0.5400 27.7 ± 4.5 0.4042
Abdominal circumference (centimeters) 104 ± 14.7 103 ± 11.3 0.7131 100 ± 10.7 0.2551
Glycemia (mg/dl) 152.5 ± 59.8 171 ± 62.5 0.6549 150 ± 53 0.8357
HbA1C (%) 7.8 ± 1.7 9 ± 2.6 0.0306** 8 ± 1.6 0.3880
Total cholesterol (mg/dl) 183.5 ± 42.9 189 ± 33.6 0.7293 193 ± 61.4 0.0244**
HDL cholesterol (mg/dl) 44 ± 10.6 44 ± 9.1 0.6037 41 ± 11.3 0.3853
LDL cholesterol (mg/dl) 105.5 ± 41.7 101.4 ± 49.6 0.9827 118 ± 61.3 0.1770
Triglycerides (mg/dl) 165.5 ± 93.2 177 ± 91.4 0.4578 177 ± 133.5 0.1252
Creatinine (mg/dl) 0.6 ± 0.3 0.8 ± 0.2 0.0255** 0.9 ± 0.3 0.0004**
Urinary albumin (mg/24 h) 5.2 ± 8.2 10.2 ± 8.1 0.2339 46 ± 158.1 0.0001**
CPR (mg/l) 2.4 ± 3.3 4.1 ± 3.3 0.1454 2 ± 3.3 0.8546
AGP (mg/dl) 80.5 ± 20.3 81 ± 29.8 0.6653 68 ± 31.4 0.0172**
TAC (%) 31.5 ± 30.2 44 ± 28.3 0.5072 13 ± 23.9 0.2116
MDA (µM) 3.7 ± 1 2.7 ± 1.5 0.1619 3.9 ± 1.2 0.5307
  1. All comparisons were performed in relation to the CONTROL
  2. * Significant difference—X 2
  3. ** Significant difference—Mann–Whitney U test