Table 2 The comparisons of metabolic manifestations in different porcine strains and dietary interventions
Strain | Age | Intervention | Body weight (kg) | Fasting glucose level | Fasting insulin level | Features | Refs. | |
|---|---|---|---|---|---|---|---|---|
Diet | Time | |||||||
Lee-Sung | 2 years | High fat high fructose | 12 months | Con: 98 Int: 153 (1.6 ×)a | Con: 3.9 mM Int: 4.4 mM (1.1 ×) | Con: 2.0 μIU/ml Int: 6.9 μIU/ml (3.5 ×) | Hyperinsulinemia, dyslipidemia, insulin resistance, intense insulin secretion (IVGTT) | Current |
Ossabaw | 5–10 months | High fat high fructoseb | 6 months | Con: 56 Int: 87 (1.6 ×) | Con: 77 mg/dl Int: 87 mg/dl (1.1 ×) | Con: 10 Int: 18 (1.8 ×) | Slight hyperinsulinemia, severe dyslipidemia, insulin resistance | [14] |
Ossabaw | 6 months | High fat high fructoseb | 6 months | Con: 54 Int: 91 (1.7 ×) | Con: 73 mg/dl Int: 80 mg/dl (1.1 ×) | Con: 5 μIU/ml Int: 21 μIU/ml (4.2 ×) | Hyperinsulinemia, severe dyslipidemia, insulin resistance | [39] |
Göttingen | 7–8 months | High fat high energy | 3 months | Con: 24 Int: 32 (1.3 ×) | Con: 3.6 mM Int: 4.3 mM (1.2 ×) | Con: 23 pM Int: 80 pM (3.5 ×) | Hyperinsulinemia, slightly increasing insulin secretion (IVGTT) | [37] |
Göttingen | 7 weeks | High fat high sucrose | 4 months | Con: ~ 14 Int: ~ 17 (1.2 ×) | Con: 4.2 mM Int: 4.7 mM (1.1 ×) | Con: 34 pM Int: 47 pM (1.4 ×) | Slight hyperinsulinemia, dyslipidemia, slightly increasing insulin secretion (IVGTT) | [38] |
Yucatan | 3 months | High fat high fructose | 7 months | Con: 40 Int: 73 (1.8 ×) | Con: ~ 2.3 mMb Int: ~ 2.8 mMc (1.2 ×) | Con: ~ 1.5 μIU/mlc Int: ~ 5 μIU/mlc (3.3 ×) | Hyperinsulinemia, dyslipidemia, insulin resistance, intense insulin secretion (IVGTT) | [40] |
Bama | 6 months | High fat high sucrose | 23 months | Con: 51 Int: 140 (2.7 ×) | Con: 6.62 mM Int: 4.99 mM (0.8 ×) | Con: 5.7 μIU/ml Int: 28.3 μIU/ml (5 ×) | Hyperinsulinemia, dyslipidemia, insulin resistance | [41] |