| |
Low-fat diet (n = 3)
|
HFHF diet (n = 4)
|
HFHF/low-fat (fold)
|
p value
|
|---|
|
Metabolic parameters
|
|
Glucose (mg/dl)
|
64.7 ± 3.0
|
72.3 ± 8.4
|
1.12
|
0.490
|
|
Insulin (pM)
|
7.3 ± 1.3
|
55.0 ± 13.0*
|
7.50
|
0.027
|
|
Triglyceride (mg/dl)
|
17.3 ± 3.8
|
81.0 ± 14.7*
|
4.68
|
0.016
|
|
NEFA (μM)
|
32.8 ± 9.7
|
155.2 ± 17.0**
|
4.73
|
0.002
|
|
Total cholesterol (mg/dl)
|
70.0 ± 5.0
|
69.5 ± 2.9
|
0.99
|
0.930
|
|
HDL-c (mg/dl)
|
41.1 ± 4.8
|
29.8 ± 1.3*
|
0.73
|
0.046
|
|
LDL&VLDL-c (mg/dl)
|
43.2 ± 2.5
|
53.9 ± 3.1
|
1.25
|
0.054
|
|
HDL/LDL&VLDL ratio
|
0.95 ± 0.12
|
0.56 ± 0.05*
|
0.59
|
0.019
|
|
Uric acid (mg/dl)
|
< 1.0
|
< 1.0
|
–
|
–
|
|
Hepatitis parameters
|
|
AST (IU/l)
|
12.0 ± 5.0
|
17.3 ± 9.0
|
1.44
|
0.667
|
|
ALT (IU/l)
|
49.3 ± 4.4
|
34.0 ± 6.4
|
0.69
|
0.128
|
- All pigs were fasted 6 h before taking blood samples
-
HFHF high-fat plus high-fructose diet, NEFA non-esterified fatty acids, HDL-c high density lipoprotein-cholesterol, LDL&VLDL-c low density and very low density lipoprotein-cholesterol, AST aspartate transaminase, ALT alanine transaminase
- * p < 0.05, ** p < 0.01, Data are expressed as means ± SEM (low-fat diet, n = 3; HFHF diet, n = 4)
