Fig. 3

The insulin response to intravenous glucose tolerance test (IVGTT) in low-fat and HFHF diet fed pigs. All pigs were subjected to IVGTT at the 9- (a) and 12- (b) month time points as in the description in Fig. 2 legend. For analyzing IVGTT results, the area under the curve (AUC) of insulin levels (c), acute insulin response (d), insulin increase rate at second phase, 10–40 min after glucose injection, (e) and 2-h postload insulin level (f) are shown. Data are expressed as means ± SEM (low-fat diet, n = 3; HFHF diet, n = 4). *p < 0.05, **p < 0.01, ***p < 0.001. NS not significant