Skip to main content

Advertisement

Table 2 Glucose tolerance and histological classification in groups according to IGI and HOMA-R

From: Analysis of factors influencing glucose tolerance in Japanese patients with non-alcoholic fatty liver disease

  n (%) Low-IGI 39 (100.0) Normal-IGI 92 (100.0) P Normal-R 35 (100.0) High-R 96 (100.0) P
Glucose tolerance
 NGT n (%) 4 (10.3) 43 (46.7) <0.0001* <0.0001** 16 (45.7) 31 (33.3) 0.1564* 0.0284**
 IGM n (%) 14 (35.9) 37 (40.2) 15 (42.9) 36 (37.5)
 DM n (%) 21 (53.8) 12 (13.1) 4 (11.4) 29 (30.2)
Histological classification
 M1 n (%) 5 (12.8) 12 (13.0) 0.5947*** 9 (25.7) 8 (8.3) 0.0338***
 M2 n (%) 10 (25.6) 28 (30.5) 11 (31.4) 27 (28.1)
 M3 n (%) 10 (25.6) 12 (13.0) 6 (17.2) 16 (16.7)
 M4 n (%) 14 (36.0) 40 (43.5) 9 (25.7) 45 (46.9)
  1. M1, M2, M3, and M4: type 1, 2, 3, and 4 in histological classification of NAFLD by Mateonni, respectively
  2. IGI insulinogenic index, low-IGI IGI ≤ 43.2 pmol/mmol (40 μU/mg), normal-IGI IGI > 43.2 pmol/mmol (40 μU/mg), normal-R HOMR-R ≤ 1.6, high-R HOMA-R > 1.6
  3. * NGT vs. IGM + DM
  4. ** NGT + IGM vs. DM
  5. *** NAFL (M1 + M2) vs. NASH (M3 + M4)