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Table 2 Glucose tolerance and histological classification in groups according to IGI and HOMA-R

From: Analysis of factors influencing glucose tolerance in Japanese patients with non-alcoholic fatty liver disease

 

n (%)

Low-IGI 39 (100.0)

Normal-IGI 92 (100.0)

P

Normal-R 35 (100.0)

High-R 96 (100.0)

P

Glucose tolerance

 NGT

n (%)

4 (10.3)

43 (46.7)

<0.0001*

<0.0001**

16 (45.7)

31 (33.3)

0.1564*

0.0284**

 IGM

n (%)

14 (35.9)

37 (40.2)

15 (42.9)

36 (37.5)

 DM

n (%)

21 (53.8)

12 (13.1)

4 (11.4)

29 (30.2)

Histological classification

 M1

n (%)

5 (12.8)

12 (13.0)

0.5947***

9 (25.7)

8 (8.3)

0.0338***

 M2

n (%)

10 (25.6)

28 (30.5)

11 (31.4)

27 (28.1)

 M3

n (%)

10 (25.6)

12 (13.0)

6 (17.2)

16 (16.7)

 M4

n (%)

14 (36.0)

40 (43.5)

9 (25.7)

45 (46.9)

  1. M1, M2, M3, and M4: type 1, 2, 3, and 4 in histological classification of NAFLD by Mateonni, respectively
  2. IGI insulinogenic index, low-IGI IGI ≤ 43.2 pmol/mmol (40 μU/mg), normal-IGI IGI > 43.2 pmol/mmol (40 μU/mg), normal-R HOMR-R ≤ 1.6, high-R HOMA-R > 1.6
  3. * NGT vs. IGM + DM
  4. ** NGT + IGM vs. DM
  5. *** NAFL (M1 + M2) vs. NASH (M3 + M4)
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Diabetology & Metabolic Syndrome

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