Skin autofluorescence, a non-invasive biomarker for advanced glycation end products, is associated with the metabolic syndrome and its individual components

Table 3 Associations for skin autofluorescence in the metabolic syndrome population

	Coefficient B	SE	p value
Univariate model
Elevated blood pressure	0.113	0.012	<0.0001
Low HDL cholesterol	−0.094	0.009	<0.001
Elevated triglycerides	0.029	0.009	0.001
Impaired fasting glucose	0.124	0.008	<0.0001
Enlarged waist circumference	0.038	0.011	0.001
Multivariate model
Elevated blood pressure	0.044	0.015	0.003
Low HDL cholesterol	0.036	0.012	0.002
Elevated triglycerides	−0.001	0.011	0.920
Impaired fasting glucose	0.008	0.012	0.502
Enlarged waist circumference	0.016	0.014	0.269
Age	0.019	0.001	1.3 × 10 ⁻¹⁵⁹
Male gender	−0.016	0.011	0.272
Creatinine clearance (mL/min)	0.001	0.0002	0.014
HbA1c (%)	0.055	0.016	2.3 × 10 ⁻⁴
Coffee consumption (cups/day)	0.024	0.002	6.6 × 10 ⁻²⁹
Current smoking^a	0.116	0.011	1.1 × 10 ⁻²³
Pack-years	0.004	0.0003	5.6 × 10 ⁻³¹
MI	0.062	0.029	0.033
CVA	0.026	0.043	0.562

Data are shown as coefficient B (standard error) per arbitrary unit (AU). The individual MetS components were included into the model as categorical variables (yes/no) while the other variables were continuous variables
Significant associations are shown in italic
CVA cerebrovascular accident, HDL high density lipoprotein, MI myocardial infarction
^aCurrent smoking vs non- and former smoking

ISSN: 1758-5996