Table 1 Baseline characteristics and patient disposition

Age (years)

62.8 ± 6.4

61 ± 5.3

0.324

Time since menopause (years)

14 ± 8.5

13.1 ± 8.1

0.740

Race, n (%)

 Caucasian

18 (85.7)

19 (90.4)

NA

 Black

2 (9.5)

1(4.8)

NA

 Hispanic or latino

1 (4.8)

1 (4.8)

NA

Physical activity, n (%)

9 (42.9)

9 (42.9)

1.000

Calcium intake (mg/day)^a

811 ± 403

824 ± 397

0.787

Metformin daily dose (mg)

1640.5 ± 664.2

1742.9 ± 626.4

0.610

Body weight (kg)

77.3 ± 15.7

82.7 ± 20.1

0.336

BMI (kg/m²)

31.7 ± 5.8

33.8 ± 6.7

0.287

Serum calcium (mg/dL)

9.3 ± 0.4

9.3 ± 0.4

0.661

Serum phosphorous (mg/dL)

3.7 ± 0.4

3.8 ± 0.5

0.512

Serum creatinine (mg/dL)

0.78 ± 0.15

0.75 ± 0.11

0.483

Vitamin D (25OH) (mg/dL)

34.7 ± 10.1

34.9 ± 19.8

0.963

Calcitonin (pg/mL)^b

<2.0

<2.0

NA

AST (U/L)

23.6 ± 9.3

30.0 ± 13.5

0.080

ALT (U/L)

29.5 ± 19.2

34.8 ± 19.2

0.373

FPG (mg/dL)

144.0 ± 22.4

146.8 ± 28.5

0.729

PPG (mg/dL)

159.4 ± 48.6

147.1 ± 54.6

0.446

HbA1c (%)/(mmol/mol)

7.35 ± 0.54/57 ± 5.9

7.32 ± 0.60/56 ± 6.6

0.851