Table 1 Clinical and biochemical variables in a sample of patients with familial partial lipodystrophy type 2 (FLPD2) in comparison to control group
FLPD (n = 14) | Control (n = 8) | P value | |
|---|---|---|---|
Age (years) | 40.0 ± 12.6 | 31.3 ± 17.7 | 0.19 |
Gender (female) | 12 | 6 | 0.60 |
Weight (kg) | 66.2 ± 10.0 | 60.1 ± 8.8 | 0.16 |
BMI (kg/m2) | 24.1 18.5–26.9 | 23.4 19.2–27.9 | 0.40 |
Waist (cm) | 81.8 ± 8.0 | 80.7 ± 10.7 | 0.79 |
Hip (cm) | 92.0 79–96 | 94.5 89–100 | 0.028 |
WHR | 0.91 ± 0.06 | 0.84 ± 0.10 | 0.08 |
BAI | 24.1 ± 2.8 | 29.0 ± 3.7 | 0.002 |
Glucose (mg/dL) | 90.5 70.0–184.0 | 89.0 81–101 | 0.56 |
Insulin (mU/L) | 11.2 4.8–42.9 | 5.3 3.1–13.3 | 0.015 |
HOMA-ß | 40.4 ± 19.2 | 21.4 ± 11.9 | 0.04 |
HOMA-IR | 2.2 1.1–18.7 | 1.1 0.6–3.3 | 0.025 |
QUICKI | 0.32 ± 0.03 | 0.37 ± 0.03 | 0.02 |
HDL (mg/dL) | 42.6 ± 10.4 | 66.1 ± 16.0 | <0.01 |
Triglycerides (mg/dL) | 184.9 ± 75.4 | 89.1 ± 51.0 | <0.01 |
HbA1c (%) | 5.6 5.2–9.1 | 5.4 4.8–6.1 | 0.14 |
DPP-4 (ng/mL) | 4.89 ± 0.92 | 3.93 ± 1.08 | 0.04 |