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Table 1 The extracted glycated hemoglobin and extracted glycated albumin data in the first repeated cross-sectional study

From: Changes in antidiabetic prescription patterns and indicators of diabetic control among 200,000 patients over 13 years at a single institution in Japan

Year 2001 2005 2010 2013 rs* p value*
Measured HbA1c (n) 10,651 14,342 18,783 7846  
HbA1c (NGSP) (%) 7.9 ± 1.4 7.9 ± 1.4 7.7 ± 1.4 7.6 ± 1.4 −0.11 <0.01
HbA1c (IFCC) (mmol/mol) 63 ± 16 63 ± 16 60 ± 15 59 ± 15   
HbA1c (NGSP) groupa       
 <6% (%) 615 (6) 471 (3) 935 (5) 511 (7)   
 ≥6% and <7% (%) 1997 (19) 2786 (19) 5194 (28) 2367 (30)   
 ≥7% and <8% (%) 3457 (33) 5238 (37) 6621 (35) 2585 (33)   
 ≥8% (%) 4582 (43) 5847 (41) 6033 (32) 2383 (30)   <0.01#
  1. Mean ± standard deviation or n (%)
  2. NGSP National Glygohemoglobin Standardization Program, IFCC The International Federation of Clinical Chemistry and Laboratory Medicine
  3. * Analysis results over 13 years; Additional file 1 shows this in detail
  4. # Using the Chi square test
  5. a Percentages in this column may not add up to exactly 100% because of rounding up
Year 2003 2005 2010 2013 rs* p value*
Measured glycated albumin (n) 8415 12,934 17,681 7463   
Glycated albumin (%) 22.7 ± 5.3 22.5 ± 5.6 21.2 ± 5.5 20.7 ± 5.7 −0.13 <0.01
Glycated albumin quartilea
 <18% (%) 1281 (15) 2348 (18) 5173 (29) 2584 (35)   
 ≥18% and <20.7% (%) 1919 (23) 3004 (23) 4501 (26) 1728 (23)   
 ≥20.7% and <24.2% (%) 2487 (30) 3737 (29) 4048 (23) 1622 (22)   
 ≥24.2% (%) 2728 (32) 3845 (30) 3959 (22) 1528 (21)   <0.01#
  1. Mean ± standard deviation or n (%)
  2. NGSP National Glygohemoglobin Standardization Program, IFCC The International Federation of Clinical Chemistry and Laboratory Medicine
  3. * Analysis results over 13 years; Additional file 1 shows this in detail
  4. # Using the Chi square test
  5. a Percentages in this column may not add up to exactly 100% because of rounding up