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Table 2 Serum adrenal hormones, endothelial, and inflammatory markers in control, obese patients with NT, pre-HT & HT

From: Association of cardiac NT pro-β-type natriuretic peptide with metabolic and endothelial risk factors in young obese hypertensive patients: a perspective on the hypothalamic pituitary adrenal axis activation

  Control-subjects (N = 30) Obese patients
  NT (N = 20) Pre-HT (N = 20) HT (N = 20)
Adrenal hormones
Cortisol (µg/dL) 9.1 ± 1.4 5.6 ± 0.7* 8.9 ± 2.4*, # 12.7 ± 0.5*, #, a
Aldosterone(µg/dL) 88.6 ± 8.5 132.1 ± 6.9* 195.9 ± 70.9*, # 320.2 ± 22.4*,#, a
ACTH(pg/ml) 23.8 ± 2.9 24.8 ± 5.6 79.6 ± 42.07*, # 44.2 ± 7.5*, #, a
NT-pro BNP(pg/ml) 73.07 ± 11.05 377.3 ± 87.8* 585.7 ± 155.7*, # 881.1 ± 130.9*, # a
Cytokine markers   
TNF-α (ng/ml) 2.3 ± 0.5 6.02 ± 1.4* 14.3 ± 7.6*, # 31.6 ± 6.7*, #, a
IL-6 (ng/ml) 1.2 ± 0.2 5.1 ± 1.2* 9.3 ± 4.6*, # 18.5 ± 2.4*, #, a
IL-23 (ng/ml) 16.1 ± 3.1 76.9 ± 6.3* 93.5 ± 15.5*, # 186.6 ± 23.5*, #, a
hs-CRP (mg/L) 0.3 ± 0.09 0.9 ± 0.12* 1.8 ± 0.9*, # 3.7 ± 0.8*, #, a
  1. Values are mean ± SD for control healthy, obese normotensive, prehypertensive and hypertensive patients groups
  2. Values (*) is significantly different from control group; (#) significantly different from normotensive obese patients, (a) significantly different from prehypertensive obese patients. Values are statistically significant at P < 0.05 using one way ANOVA with LSD as post hoc test. (SPSS program)