Skip to main content

Table 2 Treatment patterns by region and country

From: Challenges associated with insulin therapy progression among patients with type 2 diabetes: Latin American MOSAIc study baseline data

  All Mosaic cohort LA Non-LA countries p Argentina Brazil México p
Freq of insulin injections/day mean 1.63 (0.68) 1.80 (0.68) 1.60 (0.67) <0.0001 1.99 (0.76) 1.73 (0.73) 1.69 (0.54) <0.0001
Insulin regimen
 Basal insulin only
  Overall, n (%) 2168 (49.9 %) 365 (70.1 %) 1803 (47.2 %) <0.0001 103 (64.4 %) 116 (74.8 %) 146 (70.9 %) <0.0001
  Once, n (%) 1656 (76.4 %) 152 (41.6 %) 1504 (83.4 %) 37 (35.9 %) 52 (44.8 %) 63 (43.2 %)
  More than once, n (%) 512 (23.6 %) 213 (58.4 %) 299 (16.6 %) 66 (64.1 %) 64 (55.2 %) 83 (56.8 %)
 Mixed insulin only  
  Overall, n (%) 1284 (29.6 %) 70 (13.4 %) 1214 (31.8 %) 36 (22.5 %) 0 (0.0 %) 34 (16.5 %)
  Once, n (%) 112 (8.7 %) 4 (5.7 %) 108 (8.9 %) 1 (2.8 %) 0 (0.0 %) 3 (8.8 %)
  More than once, n (%) 1172 (91.3 %) 66 (94.3 %) 1106 (91.1 %) 35 (97.2 %) 0 (0.0 %) 31 (91.2 %)
 Short acting only  
  Overall, n (%) 170 (3.9 %) 11 (2.1 %) 159 (4.2 %) 1 (0.6 %) 1 (0.6 %) 9 (4.4 %)
  Once, n (%) 37 (21.8 %) 2 (18.2 %) 35 (22.0 %) 1 (100.0 %) 0 (0.0 %) 1 (11.1 %)
  More than once, n (%) 133 (78.2 %) 9 (81.8 %) 124 (78.0 %) 0 (0.0 %) 1 (100.0 %) 8 (88.9 %)
 Other insulin combinations  
  Overall, n (%) 597 (13.8 %) 64 (12.3 %) 533 (14.0 %) 20 (12.5 %) 27 (17.4 %) 17 (8.3 %)
  Once, n (%) 172 (28.8 %) 14 (21.9 %) 158 (29.6 %) 2 (10.0 %) 9 (33.3 %) 3 (17.6 %)
  More than once, n (%) 425 (71.2 %) 50 (78.1 %) 375 (70.4) 18 (90.0 %) 18 (66.7 %) 14 (82.4 %)
Other antidiabetic medication
 No. of OADs, mean (SD) 1.22 (1.09) 0.84 (0.88) 1.27 (1.10) <0.0001 0.66 (0.68) 1.33 (0.91) 0.61 (0.84) <0.0001
 Metformin, n (%) 2437 (56.1 %) 280 (53.7 %) 2157 (56.5 %) 0.2400 82 (51.3 %) 122 (78.7 %) 76 (36.9 %) <0.0001
 Sulfonylurea, n (%) 1389 (32.0 %) 92 (17.7 %) 1297 (34.0 %) <0.0001 13 (8.1 %) 55 (35.5 %) 24 (11.7 %) <0.0001
 Dipeptidyl peptidase-4 inhibitor, n (%) 538 (12.4 %) 38 (7.3 %) 500 (13.1 %) 0.0002 2 (1.3 %) 20 (12.9 %) 16 (7.8 %) 0.0003
 Alpha-glucosidase inhibitor, n (%) 321 (7.4 %) 7 (1.3 %) 314 (8.2 %) <0.0001 1 (0.6 %) 2 (1.3 %) 4 (1.9 %) 0.5536
 GLP-1, n (%) 143 (3.3 %) 5 (1.0 %) 138 (3.6 %) 0.0015 2 (1.3 %) 2 (1.3 %) 1 (0.5 %) 0.6678
 Other drug, n (%) 443 (10.2 %) 14 (2.7 %) 429 (11.2 %) <0.0001 5 (3.1 %) 5 (3.2 %) 4 (1.9 %) 0.6952
  1. GLP1 Glucagon-like peptide-1, LA Latin America, OADs oral antidiabetic drugs, SD standard deviation