Table 1 Baseline characteristics of study subgroups
From: Lixisenatide improves glycemic outcomes of Japanese patients with type 2 diabetes: a meta-analysis
Lixisenatide | Placebo | p value | Lixisenatide | Placebo | p value | |
|---|---|---|---|---|---|---|
Low (<8 %) baseline HbA1c | High (≥8 %) baseline HbA1c | |||||
N | 44 | 33 | 99 | 103 | ||
Age (years), mean (SD) | 61.2 (9.1) | 58.7 (11.3) | 0.29 | 58.0 (10.9) | 57.5 (11.3) | 0.75 |
Female-N (%) | 14 (31.8) | 8 (24.2) | 0.47 | 36 (36.4) | 36 (35.0) | 0.83 |
Duration of diabetes (years), mean (SD) | 13.1 (8.0) | 12.8 (10.0) | 0.89 | 11.3 (7.3) | 12.3 (7.4) | 0.34 |
HbA1c (%), mean (SD) | 7.53 (0.29) | 7.52 (0.29) | 0.86 | 8.88 (0.62) | 8.90 (0.58) | 0.81 |
Low (<25 kg/m2) baseline BMI | High (≥25 kg/m2) baseline BMI | |||||
|---|---|---|---|---|---|---|
N | 77 | 73 | 66 | 63 | ||
Age (years), mean (SD) | 60.9 (8.9) | 59.8 (10.9) | 0.49 | 56.7 (11.7) | 55.4 (11.4) | 0.53 |
Female-N (%) | 21 (27.3) | 24 (32.9) | 0.45 | 29 (43.9) | 20 (31.8) | 0.15 |
Duration of diabetes (years), mean, (SD) | 12.4 (7.5) | 14.1 (9.1) | 0.22 | 11.2 (7.5) | 10.5 (6.2) | 0.56 |
HbA1c (%), mean (SD) | 8.38 (0.81) | 8.41 (0.73) | 0.79 | 8.56 (0.84) | 8.74 (0.84) | 0.23 |
Short (<10 years) duration of diabetes | Long (≥10 years) duration of diabetes | |||||
|---|---|---|---|---|---|---|
N | 68 | 59 | 75 | 77 | ||
Age (years), mean (SD) | 55.9 (11.3) | 53.3 (10.4) | 0.19 | 61.8 (8.9) | 61.2 (10.8) | 0.71 |
Female-N (%) | 27 (39.7) | 16 (27.1) | 0.13 | 23 (30.7) | 28 (36.4) | 0.46 |
Duration of diabetes (years), mean (SD) | 5.5 (2.8) | 5.9 (2.2) | 0.42 | 17.7 (5.5) | 17.5 (7.2) | 0.86 |
HbA1c (%), mean (SD) | 8.52 (0.81) | 8.64 (0.86) | 0.43 | 8.41 (0.84) | 8.50 (0.74) | 0.46 |
<65 years of age | ≥65 years of age | |||||
|---|---|---|---|---|---|---|
N | 97 | 97 | 46 | 39 | ||
Age (years), mean (SD) | 53.9 (8.6) | 52.6 (8.8) | 0.30 | 69.7 (3.9) | 70.7 (4.2) | 0.25 |
Female-N (%) | 35 (36.1) | 30 (30.9) | 0.45 | 15 (32.6) | 14 (35.9) | 0.75 |
Duration of diabetes (years), mean, (SD) | 10.4 (6.9) | 10.5 (6.5) | 0.92 | 14.9 (8.0) | 17.2 (9.6) | 0.24 |
HbA1c (%), mean (SD) | 8.56 (0.83) | 8.82 (0.78) | 0.16 | 8.24 (0.87) | 8.44 (0.74) | 0.25 |