Sitagliptin monotherapy has better effect on insulinogenic index than glimepiride monotherapy in Japanese patients with type 2 diabetes mellitus: a 52-week, multicenter, parallel-group randomized controlled trial

Table 2 Post-treatment comparison of physical and chemical parameters in the full analysis set

Covariates	Glimepiride (n = 68)	Sitagliptin (n = 65)	p value^*
BMI (kg/m²)	24.5 (24.2, 24.7)	24.5 (24.3, 24.8)	0.75
HbA1c (NGSP %)	6.8 (6.7, 7.0)	6.8 (6.7, 7.0)	0.79
GA (%)	17.4 (2.8)	17.7 (2.6)	0.30
ISI (l²/mmol pmol)	15.8 (9.4, 20.8)	17.3 (11.9, 23.5)	0.046^*

Data are expressed as least-squares mean with 95 % confidence interval (CI) in BMI and HbA1c, means (SD) in GA, or median with interquartile range (IQR) in ISI
Analysis of variance (ANOVA) revealed a significant difference in the two groups
BMI body mass index, HbA1c hemoglobin A1c, GA glycated albumin, ISI insulin sensitivity index
^*Comparison of the values after 52-week treatment between glimepiride and sitagliptin groups

ISSN: 1758-5996