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Table 2 Post-treatment comparison of physical and chemical parameters in the full analysis set

From: Sitagliptin monotherapy has better effect on insulinogenic index than glimepiride monotherapy in Japanese patients with type 2 diabetes mellitus: a 52-week, multicenter, parallel-group randomized controlled trial

Covariates Glimepiride (n = 68) Sitagliptin (n = 65) p value*
BMI (kg/m2) 24.5 (24.2, 24.7) 24.5 (24.3, 24.8) 0.75
HbA1c (NGSP  %) 6.8 (6.7, 7.0) 6.8 (6.7, 7.0) 0.79
GA (%) 17.4 (2.8) 17.7 (2.6) 0.30
ISI (l2/mmol pmol) 15.8 (9.4, 20.8) 17.3 (11.9, 23.5) 0.046*
  1. Data are expressed as least-squares mean with 95 % confidence interval (CI) in BMI and HbA1c, means (SD) in GA, or median with interquartile range (IQR) in ISI
  2. Analysis of variance (ANOVA) revealed a significant difference in the two groups
  3. BMI body mass index, HbA1c hemoglobin A1c, GA glycated albumin, ISI insulin sensitivity index
  4. *Comparison of the values after 52-week treatment between glimepiride and sitagliptin groups