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Fig. 1 | Diabetology & Metabolic Syndrome

Fig. 1

From: A new compound heterozygosis for inactivating mutations in the glucokinase gene as cause of permanent neonatal diabetes mellitus (PNDM) in double-first cousins

Fig. 1

Pedigree showing inheritance of GCK mutations. Squares with vertical stripes denote males heterozygous for p.Arg447Gly, with GCK-MODY. Circles with horizontal stripes indicate females heterozygous for p.Asn254His, with GCK-MODY. Probands are indicated by arrows. N/A means data not available. Normal range for laboratorial tests: fasting blood glucose 75–99 mg/dl; serum C-peptide 0.8–4 ng/ml; haemoglobin A1c 3.9–6.1 % (19–43 mmol/mol)

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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