Fig. 7
From: Progesterone ameliorates diabetic nephropathy in streptozotocin-induced diabetic Rats
Immunohistochemistry and real-time PCR detect that progesterone replacement inhibits the AT1R expression in the diabetic kidney. A Immunohistochemical stain of the kidney sections (hematoxylin staining; magnification, ×400) show that the AT1R immunostaining (brown staining) in the glomeruli was much stronger in the D and the D-OVX groups compared with the ND group (arrows). Progesterone replacement inhibited the increase in the AT1R immunostaining in the D + OVX + P group. B AT1R mRNA expression by real-time PCR. Data represent the mean ± SEM. Means with different superscript letters are significantly different from one another (P < 0.05)