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Fig. 5 | Diabetology & Metabolic Syndrome

Fig. 5

From: DPP-4 inhibitor sitagliptin prevents inflammation and oxidative stress of heart and kidney in two kidney and one clip (2K1C) rats

Fig. 5

Effect of sitagliptin on cardiac and kidney iron deposition in 2K1C model rats. a, e Sham; b, f Sham + Sitagliptin; c, g 2K1C and d, h 2K1C + Sitagliptin. No pathological iron deposition was observed in left ventricle of heart (upper panel). Moreover, no pathological iron deposition was observed in kidneys of Sham animals (e) and Sham + Sitagliptin (f). Observe the greater iron deposition in the kidney of 2K1C rats (g arrows). No/less iron deposition can be observed in kidney of all 2K1C animals treated with sitagliptin (h). Magnification ×40. id iron deposition

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