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Table 2 The genotype distribution of rs864745 (JAZF1) and rs796158 (TSPAN8/LGR5) polymorphisms in T2DM and control group

From: Association of JAZF1 and TSPAN8/LGR5 variants in relation to type 2 diabetes mellitus in a Saudi population

 

Control n (%)

T2DM n (%)

Odds ratioa (95 % CI)

p value

Odds ratiob (95 % CI)

p value

JAZF1 (rs864745)

 AA

189 (47.25)

137 (34.25)

Reference

 

Reference

 

 AG

165 (41.25)

186 (46.5)

1.5 (1.2, 2.1)

0.004

2.1 (1.3, 3.4)

0.002

 GG

46 (11.5)

77 (19.25)

2.2 (1.4, 3.4)

0.0001

1.9 (1.2, 3.1)

0.005

 AG + GG

211 (52.75)

263 (65.75)

1.7 (1.2, 2.1)

0.0001

2.0 (1.3, 3.2)

0.001

 AA + AG

354 (89.5)

323 (80.75)

0.5 (0.3, 0.8)

0.002

0.8 (0.4, 1.5)

0.003

TSPAN8 (rs7961581)

 CC

63 (15.8)

55 (13.8)

0.90 (0.59, 1.4)

0.63

1.0 (0.66, 1.6)

0.86

 TC

138 (34.4)

153 (38.2)

1.1 (0.84, 1.4)

0.37

1.2 (0.82, 1.6)

0.41

 TT

199 (49.8)

192 (48.0)

Reference

 

Reference

 

 CC + TC

201 (50.2)

208 (52.0)

1.07 (0.81, 1.4)

0.72

1.1 (0.82, 1.5)

0.47

 TT + TC

337 (84.2)

345 (86.2)

1.1 (0.79, 1.73)

0.42

1.1 (0.81, 1.75)

0.38

  1. aCrude odds ratio (95 % CI)
  2. bOdds ratio (95 % CI) controlled for age, gender and BMI