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Table 2 Distribution (%) of the IRS-1 Arg972 gene polymorphisms in pregnant women and newborns

From: IRS-1 gene polymorphism and DNA damage in pregnant women with diabetes or mild gestational hyperglycemia

 

Pregnant women

 

Non-diabetic

MGH

Diabetic

Genotype

   

Gly/Gly

54 (87.10%)

51 (80.95%)

86 (85.15%)

Gly/Arg

08 (12.90%)

12 (19.05%)

15 (14.85%)

Allele Frequency a

   

“G” Allele

93.5%

90.4%

92.5%

“A” Allele

6.5%

9.6%

7.5%

Total

62

63

101

 

Newborns

 

Newborn of non-diabetic

Newborn of MGH

Newborn of diabetic

Genotype

   

Gly/Gly

31 (100.0%)

10 (83.33%)

32 (76.19%)

Gly/Arg

0 (0.0%)

2 (16.67%)*

10 (23.81%)*

Allele Frequency a

   

“G” Allele

100.0%

91.6%

88.1%

“A” Allele

0.0%

8.4%

11.9%

Total

31

12

42

  1. MGH: Mild gestational hyperglycemia.
  2. Data presented as N (%).
  3. aData presented as %.
  4. *p < 0.05 compared to non-diabetic group (Chi-square test).