Skip to main content

Table 1 Characteristics and metabolic profile of the mice under investigation

From: Reduced Slc2a4/GLUT4 expression in subcutaneous adipose tissue of monosodium glutamate obese mice is recovered after atorvastatin treatment

 

CTL

OB

OBA

Body weight (g)

32.9 ± 0.6

32.5 ± 0.8

32.8 ± 0.5

Lee Obesity Index (x 100)

33.1 ± 0.5

36.8 ± 0.8 **

36.0 ± 0.4**

Absolute SAT weight (g)

0.43 ± 0.08

1.69 ± 0.14 ***

1.47 ± 0.17***

Relative SAT weight (x 100) (g)

1.92 ± 0.62

5.22 ± 0.48**

4.47 ± 0.52**

Absolute VAT weight (g)

0.21 ± 0.01

1.31 ± 0.03 ***

1.35 ± 0.13 ***

Relative VAT weight (x100) (g)

0.64 ± 0.04

4.04 ± 0.16 ***

4.09 ± 0.3 ***

Plasma cholesterol (mmol/L)

1.87 ± 0.09

1.88 ± 0.13

1.33 ± 0.05** ##

Plasma glucose (mmol/L)

8.83 ± 0.27

8.4 ± 0.52

7.8 ± 0.05

Plasma insulin (pmol/L)

532.6 ± 28.5

761.8 ± 19.2***

640.3 ± 10.1* ##

kITT (%/min)

4.84 ± 0.32

2.96 ± 0.30*

4.67 ± 0.62#

Plasma AST activity (U/L)

19.6 ± 2.1

20.6 ± 2.0

21.5 ± 0.5

Plasma ALT activity (U/L)

12.6 ± 0.7

14.6 ± 1.6

15.9 ± 0.4

  1. SAT, subcutanous adipose tissue, VAT, visceral adipose tissue, kITT, glucose disappearance constant obtained in the intravenous insulin tolerance test. Data from plasma cholesterol, glucose and insulin concentration and kITT were obtained from mice subjected to 4-hour food deprivation. Data are means S.E. of 4 to 6 (morphological parameters), and 3 to 7 (metabolic hormonal parameters) animals. *P < 0.05, **P < 0.01 and ***P < 0.001 vs. CTL; #P < 0.05 and ##P < 0.01 vs. OB, One-way analysis of variance and Student–Newman–Keuls post hoc test.
Back to article page

Diabetology & Metabolic Syndrome

ISSN: 1758-5996

Contact us