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Table 2 Clinical and biochemical characteristics of patients with FCHL according to vitamin D status

From: Vitamin D concentrations in familial combined hyperlipidemia: effects of lipid lowering treatment

  Deficient (n = 46) Sufficient (n = 13) P
Age (years) 51.7 ± 10.3 44.9 ± 14.5 0.061
BMI (Kg/m2) 28.2 ± 4.0 26.8 ± 4.0 0.289
Waist (cm) 96.2 ± 10.1 93.3 ± 12.8 0.412
HbA1c (%) 5.6 ± 0.5 5.6 ± 0.4 0.838
HOMA 2.7 ± 2.4 1.8 ± 0.9 0.838
Total cholesterol (mmol/L) 6.6 ± 1.6 7.1 ± 1.3 0.335
Triglycerides (mmol/L) 2.5 (1.1-15.8) 2.0 (1.2-3.1) 0.041
LDL-c (mmol/L) 3.9 ± 1.2 4.8 ± 1.3 0.025
HDL-c (mmol/L) 1.1 ± 0.4 1.3 ± 0.3 0.051
VLDL-c (mmol/L) 1.1 (0.5-7.6) 0.9 (0.6-1.3) 0.079
NEFA (mmol/L) 0.7 (0.3-4.3) 0.5 (0.2-1.1) 0.015
ApoB (g/L) 1.3 ± 0.3 1.4 ± 0.3 0.116
LDL size (nm) 25.4 ± 0.7 25.7 ± 0.4 0.184
CRP (mg/L) 1.6 (0.3-21.1) 1.5 (0.2-21.5) 0.901
25(OH)D (nmol/L) 48.2 ± 14.3 96.9 ± 11.7 0.000
  1. P values according to T-test and Mann–Whitney test.
  2. FCHL: Familial combined hyperlipidemia, BMI: body mass index, HbA1c: glicated haemoglobin, HOMA: homeostasis model assessment, LDL-c: low-density lipoprotein cholesterol, HDL-c: high-density lipoprotein cholesterol, VLDL-c: very low-density lipoprotein cholesterol, NEFA: non-esterified fatty acids, ApoB: apolipoprotein B, CRP: C-reactive protein, 25(OH)D: 25-hydroxyvitamin D.
  3. Vitamin D deficiency = 25(OH)D ≤ 80 nmol/L.