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Table 2 Clinical and biochemical characteristics of patients with FCHL according to vitamin D status

From: Vitamin D concentrations in familial combined hyperlipidemia: effects of lipid lowering treatment

 

Deficient (n = 46)

Sufficient (n = 13)

P

Age (years)

51.7 ± 10.3

44.9 ± 14.5

0.061

BMI (Kg/m2)

28.2 ± 4.0

26.8 ± 4.0

0.289

Waist (cm)

96.2 ± 10.1

93.3 ± 12.8

0.412

HbA1c (%)

5.6 ± 0.5

5.6 ± 0.4

0.838

HOMA

2.7 ± 2.4

1.8 ± 0.9

0.838

Total cholesterol (mmol/L)

6.6 ± 1.6

7.1 ± 1.3

0.335

Triglycerides (mmol/L)

2.5 (1.1-15.8)

2.0 (1.2-3.1)

0.041

LDL-c (mmol/L)

3.9 ± 1.2

4.8 ± 1.3

0.025

HDL-c (mmol/L)

1.1 ± 0.4

1.3 ± 0.3

0.051

VLDL-c (mmol/L)

1.1 (0.5-7.6)

0.9 (0.6-1.3)

0.079

NEFA (mmol/L)

0.7 (0.3-4.3)

0.5 (0.2-1.1)

0.015

ApoB (g/L)

1.3 ± 0.3

1.4 ± 0.3

0.116

LDL size (nm)

25.4 ± 0.7

25.7 ± 0.4

0.184

CRP (mg/L)

1.6 (0.3-21.1)

1.5 (0.2-21.5)

0.901

25(OH)D (nmol/L)

48.2 ± 14.3

96.9 ± 11.7

0.000

  1. P values according to T-test and Mann–Whitney test.
  2. FCHL: Familial combined hyperlipidemia, BMI: body mass index, HbA1c: glicated haemoglobin, HOMA: homeostasis model assessment, LDL-c: low-density lipoprotein cholesterol, HDL-c: high-density lipoprotein cholesterol, VLDL-c: very low-density lipoprotein cholesterol, NEFA: non-esterified fatty acids, ApoB: apolipoprotein B, CRP: C-reactive protein, 25(OH)D: 25-hydroxyvitamin D.
  3. Vitamin D deficiency = 25(OH)D ≤ 80 nmol/L.