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Table 2 Fasting blood Triglyceride level

From: Blood glucose lowering activity of aloe based composition, UP780, in alloxan induced insulin dependent mouse diabetes model

Group

Dose (mg/kg)

Triglyceride (mg/dl)

 

Pre-induction

Post-induction

Week-2

Week-4

(Mean + SE)

(Mean + SE)

(Mean + SE)

(Mean + SE)

Vehicle (-alloxan)

0

125.1 ± 10.7

90.1 ± 3.7

119.7 ± 4.6

126.9 ± 10.6

UP780 (-)

2000

118.1 ± 8.5

92.3 ± 3.6

128.7 ± 6.4

110.5 ± 5.5

Vehicle (+alloxan)

0

141.1 ± 7.3

111.5 ± 37.6

167.8 ± 20.0

144.0 ± 14.2

Glyburide (+)

5

135.3 ± 32.0

134.6 ± 37.5

135.6 ± 48.4

163.1 ± 38.8

UP780 (+)

2000

133.5 ± 7.8

117.5 ± 10.0

124.0 ± 8.8*

124.3 ± 8.2*

UP394 (+)

80

135.2 ± 8.2

121.3 ± 16.1

116.6 ± 8.41*

128.2 ± ±11.7

Qmatrix (+)

1920

130.5 ± 10.1

101.4 ± 7.3

119.7 ± 17.1

113.8 ± 30.3*

  1. Insulin dependent diabetes was induced by administering a single intraperitoneal injection of alloxan monohydrate at a dose of 150 mg/kg to CD-1 mice. Measurements for fasting blood triglyceride were taken at pre-induction, week-0 (baseline), week-2 and week-4 after treatment. Data are expressed as mean ± SD. *P ≤ 0.05.
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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