Blood glucose lowering activity of aloe based composition, UP780, in alloxan induced insulin dependent mouse diabetes model

Table 1 Oral glucose tolerance test blood glucose values

Insulin dependent diabetes was induced by administering a single intraperitoneal injection of alloxan monohydrate at a dose of 150 mg/kg to CD-1 mice. Oral glucose tolerance test (OGTT) was conducted 4-week after onset of treatment. On the test day, animals (N = 15/group) were fasted for 5 hours and received oral administration of glucose at a dose of 2 g/kg. Blood glucose levels were determined at time 0 (before glucose injection), and at 30, 60, 90, and 120 minutes post glucose delivery. Blood samples were obtained from the tail. Data are expressed as mean ± SD. * P ≤ 0.05.

ISSN: 1758-5996