Table 6
Logistic regression analysis when MS was used as a dependent variable, and age, sex, TSF, waist/hip ratio, insulin, leptin,
LEPR
Gln223Arg,
LEP
G2548A and
BDNF
Val66Met, were taken as independent variables
From: Measurement of the levels of leptin, BDNF associated with polymorphisms LEP G2548A, LEPR Gln223Arg and BDNF Val66Met in Thai with metabolic syndrome
Variables | β | p-value | OR | (95% CI) |
---|
Leptin | 0.46 | 0.007* | 1.91 | 1.25-3.03 |
LEPR Gln223Arg | 2.37 | 0.033* | 9.07 | 1.22-37.14 |
Waist/hip ratio | 5.58 | <0.001* | 22.04 | 2.42-91.36 |
TSF | 0.17 | 0.029* | 1.31 | 1.03-1.95 |
Sex | -2.34 | 0.335 | 0.20 | 0.02-6.26 |
Age | 0.03 | 0.625 | 0.97 | 0.89-1.14 |
Insulin | 0.07 | 0.101 | 1.10 | 0.98-1.21 |
BDNF Val66Met | 0.88 | 0.179 | 2.39 | 0.74-8.54 |
LEP G2548A | 1.84 | 0.124 | 6.03 | 0.80-26.11 |
- Abbreviation: LEP leptin gene, LEPR leptin receptor gene, BDNF Brain-derived neurotrophic factor gene, TSF triceps skin-fold thickness.
- Significant level; *= p < 0.05.