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Table 3 Comparison of socio-demographic factors and glucose control of hypertensive patients with and without diabetes who were statins users or non-users

From: Statins use is associated with poorer glycaemic control in a cohort of hypertensive patients with diabetes and without diabetes

 

Hypertensive patients with DM (n = 507)

Hypertensive patients without DM (n = 553)

Statin users

Statin non users

P value (95% CI)

Statin users

Statin non users

P value (95% CI)

n = 415

n = 92

n = 396

n = 157

Age (years) Mean (SD)

61.71 (9.29)

62.17 (12.02)

0.728* (-2.176, 3.107)

62.80 (10.30)

60.52 (12.23)

0.039* (-4.463, -0.111)

Gender n (%)

      

Men

176 (84.6)

32 (15.4)

0.178**

155 (70.8)

64 (29.2)

0.725**

Women

239 (79.9)

60 (20.1)

 

241 (72.2)

93 (27.8)

 

Ethnicity n (%)

      

Malay

137 (83.5)

27 (16.5)

0.737**

116 (73.0)

43 (27.0)

0.808**

Chinese

160 (80.4)

39 (19.6)

 

220 (71.0)

90 (29.0)

 

Indian

115 (81.6)

26 (18.4)

 

54 (70.1)

23 (29.9)

 

Others

3 (100.0)

0 (0.0)

 

6 (85.7)

1 (14.3)

 

Duration of diabetes (years)

n = 406

n = 84

    

Mean (SD)

8.169 (6.556)

7.020 (6.255)

0.141*

   

HbA1c#

n = 372

n = 77

 

n = 72

n = 33

 

Mean IFCC unit (SD) mmol/mol

62 (19)

57 (17)

0.030* (-9.610, -0.494)

44 (5)

42 (6)

0.082* (-3.972, 0.242)

Mean NGSP unit (SD)%

7.8 (1.7)

7.3 (1.6)

0.034* (-0.871, -0.034)

6.1 (0.4)

6.0 (0.5)

0.089* (-0.363, 0.026)

FBG#

n = 397

n = 87

 

n = 350

n = 131

 

Mean (SD) mmol/L

7.71 (2.98)

7.25 (2.55)

0.179* (-1.142, 0.213)

5.39 (0.53)

5.27 (0.58)

0.029* (-0.231, -0.012)

TG#

n = 383

n = 84

 

n = 361

n = 137

 

Mean (SD) mmol/L

1.602 (0.737)

1.965 (1.289)

0.014* (0.075, 0.653)

1.416 (0.623)

1.357 (0.628)

0.346* (-0.182, 0.064)

HDL#

n = 383

n = 84

 

n = 361

n = 137

 

Mean (SD) mmol/L

1.269 (0.317)

1.204 (0.322)

0.092* (-0.140, 0.011)

1.465 (0.420)

1.373 (0.380)

0.026* (-0.173,-0.011)

Body Mass Index

n = 232

n = 44

 

n = 150

n = 58

 

Mean (SD) Kg/m2

28.02 (5.37)

27.74 (4.70)

0.744* (-1.990, 1.423)

27.44 (4.67)

26.73 (5.35)

0.350* (-2.189, 0.778)

Diabetic medication n (%)

      

Yes

391 (83.7)

76 (16.3)

<0.001**

   

No

24 (60.0)

16 (40.0)

    

On diuretic and/or beta-blocker n (%)

      

Yes

201 (80.1)

50 (19.9)

0.305**

196 (74.5)

67 (25.5)

0.148**

No

214 (83.6)

42 (16.4)

 

200 (69.0)

90 (31.0)

 
  1. DM = Diabetes mellitus; HbA1c = Glycated haemoglobin; FBG = Fasting blood glucose; TG = Triglyceride; HDL = HDL-Cholesterol.
  2. IFCC = International Federation of Clinical Chemistry; NGSP = National Glycohemoglobin Standardization Program.
  3. # Most recent result in the past one year.
  4. *Independent sample t-test.
  5. **Chi-square test.