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Table 3 Comparison of socio-demographic factors and glucose control of hypertensive patients with and without diabetes who were statins users or non-users

From: Statins use is associated with poorer glycaemic control in a cohort of hypertensive patients with diabetes and without diabetes

  Hypertensive patients with DM (n = 507) Hypertensive patients without DM (n = 553)
Statin users Statin non users P value (95% CI) Statin users Statin non users P value (95% CI)
n = 415 n = 92 n = 396 n = 157
Age (years) Mean (SD) 61.71 (9.29) 62.17 (12.02) 0.728* (-2.176, 3.107) 62.80 (10.30) 60.52 (12.23) 0.039* (-4.463, -0.111)
Gender n (%)       
Men 176 (84.6) 32 (15.4) 0.178** 155 (70.8) 64 (29.2) 0.725**
Women 239 (79.9) 60 (20.1)   241 (72.2) 93 (27.8)  
Ethnicity n (%)       
Malay 137 (83.5) 27 (16.5) 0.737** 116 (73.0) 43 (27.0) 0.808**
Chinese 160 (80.4) 39 (19.6)   220 (71.0) 90 (29.0)  
Indian 115 (81.6) 26 (18.4)   54 (70.1) 23 (29.9)  
Others 3 (100.0) 0 (0.0)   6 (85.7) 1 (14.3)  
Duration of diabetes (years) n = 406 n = 84     
Mean (SD) 8.169 (6.556) 7.020 (6.255) 0.141*    
HbA1c# n = 372 n = 77   n = 72 n = 33  
Mean IFCC unit (SD) mmol/mol 62 (19) 57 (17) 0.030* (-9.610, -0.494) 44 (5) 42 (6) 0.082* (-3.972, 0.242)
Mean NGSP unit (SD)% 7.8 (1.7) 7.3 (1.6) 0.034* (-0.871, -0.034) 6.1 (0.4) 6.0 (0.5) 0.089* (-0.363, 0.026)
FBG# n = 397 n = 87   n = 350 n = 131  
Mean (SD) mmol/L 7.71 (2.98) 7.25 (2.55) 0.179* (-1.142, 0.213) 5.39 (0.53) 5.27 (0.58) 0.029* (-0.231, -0.012)
TG# n = 383 n = 84   n = 361 n = 137  
Mean (SD) mmol/L 1.602 (0.737) 1.965 (1.289) 0.014* (0.075, 0.653) 1.416 (0.623) 1.357 (0.628) 0.346* (-0.182, 0.064)
HDL# n = 383 n = 84   n = 361 n = 137  
Mean (SD) mmol/L 1.269 (0.317) 1.204 (0.322) 0.092* (-0.140, 0.011) 1.465 (0.420) 1.373 (0.380) 0.026* (-0.173,-0.011)
Body Mass Index n = 232 n = 44   n = 150 n = 58  
Mean (SD) Kg/m2 28.02 (5.37) 27.74 (4.70) 0.744* (-1.990, 1.423) 27.44 (4.67) 26.73 (5.35) 0.350* (-2.189, 0.778)
Diabetic medication n (%)       
Yes 391 (83.7) 76 (16.3) <0.001**    
No 24 (60.0) 16 (40.0)     
On diuretic and/or beta-blocker n (%)       
Yes 201 (80.1) 50 (19.9) 0.305** 196 (74.5) 67 (25.5) 0.148**
No 214 (83.6) 42 (16.4)   200 (69.0) 90 (31.0)  
  1. DM = Diabetes mellitus; HbA1c = Glycated haemoglobin; FBG = Fasting blood glucose; TG = Triglyceride; HDL = HDL-Cholesterol.
  2. IFCC = International Federation of Clinical Chemistry; NGSP = National Glycohemoglobin Standardization Program.
  3. # Most recent result in the past one year.
  4. *Independent sample t-test.
  5. **Chi-square test.