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Table 3 Comparison of patients characteristics according to glucometabolic state

From: Mandatory oral glucose tolerance tests identify more diabetics in stable patients with chronic heart failure: a prospective observational study

 

NGT n = 11

Prediabetes n = 31

Diabetes n = 14

p

Age (years)

64 ± 17

69 ± 11

70 ± 11

.58

Sex (% male)

91

58

64

.15

BMI (kg/m2)

25.1 ± 3.7

27.6 ± 5.5

29.9 ± 9.7

.39

Aetiology (% IHD)

27

32

57

.22

NYHA class (% I-II-III)

55-36-9

23-48-29

21-57-21

.34

LVEF (%)

43 ± 13

42 ± 12

40 ± 12

.71

E/E’ (n = 5, n = 13, n = 7)

21.4 ± 19.4

21.2 ± 11.0

15.0 ± 8.7

.33

ACE-inhibitor or AIIA (%)

100

74

86

.16

  % optimal daily dosage

73 ± 26

96 ± 32

88 ± 61

.15

Selective β-blocker (%)

73

77

86

.75

  % optimal daily dosage

41 ± 17

52 ± 27

52 ± 25

.56

Non-selective β -blocker (%)

18

13

7

.75

  % optimal daily dosage

150 ± 71

137 ± 75

50 ± 0

.40

Diuretic (%)

64

84

71

.32

  % usual daily dosage

113 ± 67

103 ± 73

129 ± 106

.75

BNP (pg/mL)

167 ± 120

177 ± 207

293 ± 383

.39

HbA1c (%)

5.3 ± 0.2

5.7 ± 0.3

5.9 ± 0.3

.01 *

Total cholesterol (mg/dL)

176 ± 39

173 ± 45

169 ± 53

.81

HDL cholesterol (mg/dL)

43 ± 11

50 ± 15

49 ± 15

.39

LDL cholesterol (mg/dL)

107 ± 29

93 ± 32

88 ± 42

.25

Triglycerides (mg/dL)

131 ± 35

159 ± 101

160 ± 88

.94

Body weight (kg)

76.5 ± 15.8

76.5 ± 16.5

82.9 ± 30.0

.10

Fat mass (%)

31.1 ± 6.9

35.2 ± 9.1

34.8 ± 9.2

.52

Lean mass (kg)

52.2 ± 9.3

49.3 ± 9.7

52.2 ± 12.4

.62

Fat trunk/fat limb ratio

1.28 ± 0.39

1.39 ± 0.26

1.63 ± 0.35

.03**

Extension strength (Nm/kg)

    

  45°

16.8 ± 6.1

13.9 ± 2.9

13.7 ± 5.1

.32

  90°

16.6 ± 3.0

15.4 ± 4.1

15.3 ± 6.4

.58

Flexion strength (Nm/kg)

    

  45°

9.0 ± 2.8

8.2 ± 2.2

7.8 ± 3.4

.89

  90°

7.5 ± 2.2

6.7 ± 1.9

6.2 ± 2.4

.60

Self-reported physical activity (METminutes/day)

1921 (533-4313)

1872 (1789-4047)

1219 (664-5686)

.73

  1. BMI, body mass index; BNP, B-type natriuretic peptide; IHD, ischaemic heart disease; LVEF, left ventricular ejection fraction; NGT, normal glucose tolerance; NYHA, New York heart association functional class. Extension and flexion strength are expressed as peak torque relative to lean tissue of the right leg. Continuous variables are presented as mean ± SD, physical activity is presented as mean and 95% confidence interval. Categorical variables are presented as number and percentage.
  2. *NGT versus prediabetes and diabetes, **post hoc differences not significant after Bonferroni correction.