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Table 1 Serum parameters in mice

From: Liraglutide counteracts obesity and glucose intolerance in a mouse model of glucocorticoid-induced metabolic syndrome

  Experimental groups
Vehicle/PBS GC/PBS Vehicle/Lira GC/Lira
Corticosterone (ng/ml) 6.72 ± 2.29 46.56 ± 4.78* 7.83 ± 2.18 65.29 ± 10.6*
Corticotropin (pg/ml) 122 ± 14 45 ± 8* 134 ± 18 39 ± 14*
NEFA (mmol/L) 0.86 ± 0.04 1.30 ± 0.11* 0.92 ± 0.07 1.22 ± 0.14
Cholesterol (mmol/L) 2.84 ± 0.19 5.29 ± 0.46* 2.61 ± 0.12 4.16 ± 0.68*
Triglycerides (mmol/L) 1.26 ± 0.06 4.13 ± 1.10* 1.39 ± 0.15 2.98 ± 0.75
  1. Male C57Bl/6J mice were treated with 1% ethanol (vehicle) or 100 μg/ml corticosterone (GC) via their drinking water together with once-daily injections of either PBS or liraglutide (Lira) at a final dose of 0.3 mg per kg body weight for five consecutive weeks (n = 5-6). At the end of the study, blood was collected by heart puncture and serum was obtained. Serum levels for the indicated parameters are shown as mean ± s.e.m. A * denotes a significant (p < 0.05) effect of corticosterone treatment.