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Table 1 Premorbid cardiovascular risk factors, clinical characteristics and medication

From: Immune-inflammatory markers and arterial stiffness indexes in subjects with acute ischemic stroke with and without metabolic syndrome

Variable

Stroke pts with metabolic syndrome (n: 130)

Stroke pts without metabolic syndrome (n: 127)

Controls (n: 109)

P

Age (years)

64 (61-72.5)

72 (69-83.5)

69 (63-80)

0.031

M/F (n)

69/61

60/67

54/55

0.027

SBP/DBP (mm/Hg)

152±7.9/98±6.2

147±8.9/92±3.2

141±9.8/91±2.2

<0.001

diabetes (n/%)

63 (48.46)

39 (30% )

47 (41.28%)

0.263

Hypertension (n/%)

66 (50.79%)

47 (37%)

48 (44.03%)

0.301

Glucose blood levels (mg/dl)

149.3 (97-186)

129.1 (88-142)

102 (81.5-133.5)

<0.001

Cholesterol blood levels (mg/dl)

241 (189-270)

222 (179-245)

210 (167-225)

<0.001

Triglyceride blood levels (mg/dl)

197.5 (149.75-210.75)

157.5 (119.4-181.75)

167.5 (139.4-192.1)

0.004

White blood cells (per mm³)

9100 (6200-11000)

8200 (7100-10500

7400 (6500-9800)

<0.001

Stroke subtype

    

  • LAAS

49 (37.69)

52 (40.94)

  

  • Lacunar

45 (34.61)

37 (29.7)

  

  • CEI

32 (24.61)

35 (27.55)

  

  • ODE

3 (2.3)

2 (1.57)

  

  • UDE

1 (0.76)

1 (0.78)

  

AIx (%)

105 ± 3.5

101 ± 4.1

89 ± 4.6

<0.001

PWV (m/s)

12.9 ± 3.3

11.2 ± 3.2

10.02 ± 2.29

<0.001

SSS

27.12±16.21

29.65±19

30±16.21

 

IL-1-beta (pg/ml)

10 (6-11)

8 (5-16)

4 (2-5)

<0.001

IL-6 (pg/ml)

12 (9-31)

10.3 (7-29)

8 (3.1-12)

<0.001

TNF-α (pg/ml)

35.5 (10.25-46)

26 (10.55-49)

5.1 (1.1-4.3)

<0.001

E-selectin (ng/ml)

4.05 (2.0-5.8)

2.1 (1.0-3.8)

2 (1-2)

<0.001

P-selectin (ng/ml)

6.5 (3-8.9)

4.5 (2-6.8)

3,1 (2.1-4)

0.004

VICAM-1 (ng/ml)

18 (12.1-23)

16 (10.1-20)

10 (7-15)

<0.001

ICAM-1 (ng/ml)

17.8 (12.2-20)

13.5 (12.2-20)

10.9 (12-16.1)

<0.001

IL-10 (pg/ml)

2.05 (2-7)

3.15 (2-7)

5 (2-10)

0.031

vWF (ng/ml)

11 (6-15)

4 (3-9)

2 (1-5)

0.0001

PAI-1 (pg/ml)

137 (99.5-155)

23 (11-24)

15 ( 7-22)

<0.001

TPA (pg/ml)

21 (10.55-39)

55 (29-88)

11 (8-19)

0.44

CHF (n/%)

23 (17.69)

20 (15.74)

15 (14.70)

0.065

  1. SBP: systolic blood pressure; DBP: diastolic blood pressure; MAP: mean arterial pressure; AIx: augmentation index; PWV: pulse wave velocity; SSS: Scandinavian Stroke Scale score; NIHSS: National Institutes of Health Stroke Scale; Angiotensin II receptor blockers (ARBs); CAD: coronary artery disease; CHF: congestive heart failure; TIA: transitory ischemic attack; LVH: left ventricular hypertrophy; WMHLS: white matter hypertension lesions.
  2. Demographic and history data are expressed as n° (percentage).
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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